University Of Pittsburgh
Clinical trials sponsored by University Of Pittsburgh, explained in plain language.
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New moms shed pounds with sleep-focused online program
Disease control CompletedThis study tested a 16-week online program called Sleep GOALS to help new mothers lose weight by improving their sleep, diet, and physical activity. Forty postpartum women with a BMI over 25 and poor sleep were enrolled. The program provided strategies and self-monitoring tools t…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Home visits help new moms fight heart risks after baby
Disease control CompletedThis study tested a program called Family Check-Up Heart, which adds heart-health coaching to regular home visits for new moms and their babies. About 150 mothers who had Medicaid and recently gave birth took part. The goal was to see if the program could help moms manage weight,…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Can a team approach help IBD patients with anxiety and depression?
Disease control CompletedThis study tested two team-based care models for 657 adults with inflammatory bowel disease (Crohn's or ulcerative colitis) who also had mild to severe behavioral health symptoms. One model used in-person visits with a team including a gastroenterologist, nurse, nutritionist, and…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Disease control
Last updated Jun 26, 2026 13:18 UTC
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Can a fitness tracker and online coaching prevent heart disease?
Prevention CompletedThis study tested a 1-year online program designed to help adults aged 40-70 who are at risk for heart disease become more physically active. Participants either received a fitness tracker plus online coaching and goal-setting sessions, or just a fitness tracker with standard act…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated Jun 27, 2026 12:31 UTC
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Can a community program stop youth violence? new study says yes
Prevention CompletedThis study tested a program called Creating Peace that helps teens aged 14-19 learn to prevent violence and address racism. Over 500 teens took part in community groups. The program aimed to reduce physical, sexual, and emotional violence, as well as weapon carrying, by teaching …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated Jun 27, 2026 11:01 UTC
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Lifestyle coaching may ward off depression in widowed seniors
Prevention CompletedThis study tested whether a 12-week healthy lifestyle program could prevent depression in older adults who recently lost a spouse. Participants used digital tools to track sleep, meals, and activity, plus received weekly health coaching. The goal was to see if this approach reduc…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated Jun 27, 2026 09:00 UTC
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Can a 6-Week family program stop dating violence in latine teens?
Prevention CompletedThis pilot study tested a 6-week family-based program called Juntos to prevent dating violence among Latine adolescents aged 12-16 and their caregivers. 41 families in Pittsburgh were randomly assigned to the program or a resource guide. The study measured how acceptable and feas…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated Jun 27, 2026 08:12 UTC
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Lifestyle makeover may stave off dementia in At-Risk seniors
Prevention CompletedThis study looked at how common mild cognitive impairment is among adults aged 50-65 in Kerala, India, and tested a one-month program combining nutrition advice, exercise, brain games, social support, and heart health management. The goal was to see if this approach is practical …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Prevention
Last updated Jun 27, 2026 08:01 UTC
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Can video chats help young adults with diabetes stay on track?
Symptom relief CompletedThis study tested a group telehealth program called TREAT-ED for young adults aged 18-26 with type 1 diabetes. The program used video sessions led by a diabetes educator to teach self-management skills. The goal was to see if this approach could improve participation in diabetes …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Study finds way to cut unneeded meds in mental health patients
Symptom relief CompletedThis study tested a program to reduce anticholinergic medications (like benztropine) in 53 adults with schizophrenia, bipolar disorder, or other serious mental illnesses who had been taking these drugs for at least 6 months. The goal was to safely taper or stop these medications …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Bringing eating disorder treatment home: a new hope for teens
Symptom relief CompletedThis study tested two types of talk therapy for teenagers with anorexia nervosa, delivered at home instead of a clinic. 77 teens and their families participated to see if home-based treatment is effective and acceptable. The goal was to improve weight, eating habits, and family s…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Early walking after hip surgery may speed recovery, study finds
Symptom relief CompletedThis study tested whether letting people put weight on their hip as soon as they can after hip labral repair and femoroplasty helps them recover faster. 49 participants were followed after surgery to see if early weight bearing improved hip function and quality of life without ca…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Can better sleep help depressed teens? small study tests new program
Symptom relief CompletedThis study tested a behavioral sleep program for 16 depressed teenagers who slept less than 7 hours on school nights or had irregular sleep schedules. The program included one session with a provider and used smartphone tools to help teens create a plan for longer and more regula…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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Better sleep for cancer patients and their partners: a new approach
Symptom relief CompletedThis study tested a sleep improvement program for people with cancer and their intimate partners who also have sleep problems. The goal was to reduce insomnia and improve sleep quality. Only 2 couples took part, so results are very limited.
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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New training helps stroke survivors regain awareness after neglect
Symptom relief CompletedThis study tested a metacognitive strategy training for 45 stroke survivors who have trouble paying attention to one side of their world (called neglect). The training aimed to improve their self-awareness and ability to do daily tasks. Results will show if this approach reduces …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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New online program aims to beat cancer fatigue
Symptom relief CompletedThis study tested a program called Maximizing Energy to help women who finished breast cancer treatment manage their fatigue. Fifteen women took part, either in the program or a general health education group, over six online sessions. Researchers checked if women stayed in the s…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Brain training for daily life: new approach may help seniors with memory loss
Symptom relief CompletedThis study tested whether a program called Strategy Training can help older adults with mild cognitive impairment (MCI) manage everyday tasks like shopping, paying bills, and taking medication. The training, delivered by occupational therapists, teaches goal-setting, scheduling, …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Mindfulness during pregnancy may ease stress and depression
Symptom relief CompletedThis study tested whether an 8-week mindfulness-based cognitive therapy (MBCT) program can reduce stress, anxiety, and depression in pregnant women at risk for psychological distress. 84 women participated, with some receiving MBCT and others getting usual care. The goal was to u…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Apple watch and health coaching aim to ease caregiver burden
Symptom relief CompletedThis study tested whether an Apple Watch paired with a special app and weekly health coaching could help dementia caregivers improve their sleep and mood. Twenty-one caregivers wore the watch to track their activity and sleep, and received personalized feedback and motivational c…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Can a nap room and fancy glasses save night shift nurses from burnout?
Symptom relief CompletedThis small pilot study tested whether giving night shift nurses access to a napping/relaxation room and blue/green light blocking glasses is practical and might improve their health and reduce burnout. Five nurses from one hospital took part. The study focused on whether nurses w…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New online training boosts brain power for young cancer survivors
Symptom relief CompletedThis study tested a modified telehealth program called MAAT-YS for young adult survivors of childhood cancer (ages 18-39) who have memory or attention problems from their past treatment. Seven participants completed 8 weekly video sessions and homework to improve their cognitive …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Mindfulness app might lower stress in trauma survivors
Symptom relief CompletedThis small study tested a 10-week online mindfulness program in 15 young adults (ages 18-29) who experienced childhood trauma. Participants took group mindfulness classes online and reported their stress levels and gave blood samples before and after the program. The goal was to …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Yoga may spark positive growth after concussion in women
Symptom relief CompletedThis study explored whether a 6-week online yoga program could help women who had a mild concussion experience post-traumatic growth — positive psychological changes like finding new meaning or strength. 27 women from a Facebook group took part. The yoga sessions included gentle …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Brain zaps boost balance in breast cancer survivors
Symptom relief CompletedThis pilot study tested whether a non-invasive brain stimulation technique called tDCS could improve balance and thinking in older women who had chemotherapy for breast cancer. 48 women aged 50-85 took part. The results will show if this approach can help with common side effects…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Does washing fat before facial grafting give better skin results?
Symptom relief CompletedThis study looked at whether washing fat with saline before injecting it into the face improves skin appearance more than using unwashed fat. Twenty-six healthy women aged 35 to 70 with visible signs of aging received fat grafts on both sides of their face. Researchers measured c…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Texts and cash incentives get teens moving in prediabetes study
Symptom relief CompletedThis study tested whether daily text messages and small financial rewards could motivate overweight teens and young adults with prediabetes or type 2 diabetes to be more physically active. 75 participants wore a Fitbit and received different combinations of texts and incentives o…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New targeted therapy shows promise for concussion sufferers
Symptom relief CompletedThis study tested a personalized treatment plan for people with mild traumatic brain injury (concussion) that targets specific symptoms like anxiety, headaches, vision problems, and sleep issues. 169 adults with recent concussions were assigned to either the targeted treatment or…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Can simple guides curb opioid misuse? new study tests doctor tools
Knowledge-focused CompletedThis study tested whether doctors can use simple decision guides to better manage opioid misuse behaviors in patients on long-term opioid therapy for chronic pain. Researchers worked with 49 clinicians at community clinics to see if the guides were easy to use and helpful. The go…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jul 01, 2026 22:00 UTC
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Can walking on a split treadmill reveal secrets of aging balance?
Knowledge-focused CompletedThis study looked at how older adults (65+) adapt their walking when one leg moves faster than the other on a split-belt treadmill. Researchers measured brain activity and balance to understand the link between automatic walking and mobility. The goal was to learn more about how …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Can training doctors help pregnant women with opioid addiction get better care?
Knowledge-focused CompletedThis study tested a training program for prenatal healthcare providers to help them use medication-assisted treatment (MAT) for opioid use disorder during pregnancy. Researchers looked at data from over 1,000 patients to see if the program increased use of MAT and improved health…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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New digital tool may help doctors spot and stop teen suicide risk
Knowledge-focused CompletedThis study tested a digital suicide prevention program for teens in pediatric primary care. Thirty at-risk youth aged 12-17 and their parents used the tool, which helps doctors identify and address suicidal thoughts and behaviors. The goal was to see if the program is practical a…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Could a simple kit make telemedicine for sick kids easier?
Knowledge-focused CompletedThis pilot study gave 100 families of infants a kit with a thermometer, pulse oximeter, ear scope, and swab tests to use during telemedicine visits. The goal was to see if families would use the kit and find it helpful. Researchers measured how many families stayed in the study a…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Remote coaching boosts Clinicians' wheelchair training skills
Knowledge-focused CompletedThis study tested whether a remote training program helps rehabilitation professionals teach manual wheelchair users how to use their chairs more safely and effectively. 235 clinicians took part and were split into three groups: one received remote feedback, one did structured se…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Brain scans reveal why bladder control fails with age
Knowledge-focused CompletedThis completed study looked at how the brain controls the bladder in older women with urgency urinary incontinence. Researchers used MRI scans to compare brain activity during bladder filling and emptying in 207 women, both young and old, with and without incontinence. The goal w…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Video game trains ER doctors to save trauma patients
Knowledge-focused CompletedThis study tested whether a custom video game called Night Shift can improve how emergency physicians follow trauma triage guidelines. 800 board-certified doctors who work in non-trauma center ERs across the US participated. Some played the game for 2 hours initially and then 20 …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Can palliative care help older ICU patients and their families?
Knowledge-focused CompletedThis study looked at whether adding specialty palliative care early on to standard intensive care can improve the experience for critically ill older adults (age 60+) and their families. Over 1,000 patients and their family members took part. The goal was to see if this approach …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New web tool aims to ease tough ICU decisions for families of older patients
Knowledge-focused CompletedThis study tested a web-based tool to support family members who make medical decisions for critically ill older adults unable to speak for themselves. The tool provided information about the ICU, helped families prepare for meetings with doctors, and shared their questions and c…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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New study tests if hands-on therapy can keep older adults out of the operating room
Knowledge-focused CompletedThis study looked at whether manual therapy, exercise, and acupuncture can reduce pain and improve walking in older adults with lumbar spinal stenosis, a common cause of back and leg pain. Researchers enrolled 60 participants to see if a larger trial is possible. The goal is to f…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Balance therapy study seeks clues to who recovers best
Knowledge-focused CompletedThis study looked at 52 adults with dizziness and balance problems from a one-sided inner ear disorder. Researchers measured how well people functioned before and after a standard balance therapy program. The goal was to see if things like dizziness severity or personal factors c…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Medical records reveal clues to rare genetic disease in amish and mennonite populations
Knowledge-focused CompletedThis study looked back at the medical records of 38 people who have a specific genetic form of propionic acidemia, a rare metabolic disorder. The goal was to describe how the condition progresses over time, especially heart problems, and to create a better plan for preventive car…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Which advance care planning method works best for cancer patients?
Knowledge-focused CompletedThis study looked at two ways to help people with advanced cancer plan their future medical care: one-on-one talks with a trained nurse or social worker (in person or by phone), or using a website on their own. Over 600 patients took part to see which method helped them think abo…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Lung transplant infection study aims to improve Long-Term survival
Knowledge-focused CompletedThis study followed 600 lung transplant recipients at the University of Pittsburgh to see how common viral and bacterial infections are and how they affect long-term health. Researchers focused on whether a specific infection (C. pneumoniae) is linked to a condition called bronch…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Brain scans in babies could predict future development
Knowledge-focused CompletedThis completed study looked at 557 newborns with brain injury to see if advanced MRI scans can predict their future thinking and learning abilities. Researchers compared MRI results with developmental tests taken over time. The goal is to find better ways to screen and treat brai…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Formula showdown: which one helps sick Kids' gut bugs?
Knowledge-focused CompletedThis study compared two types of liquid food (Pediasure and Nourish) to see how they affect the gut bacteria in 32 critically ill children ages 1-17 in the ICU. Researchers collected stool and saliva samples to track changes in the microbiome. The goal was to understand how diffe…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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App tracks happiness in young transplant patients
Knowledge-focused CompletedThis study tested a smartphone app to collect quality-of-life reports from children who had a liver transplant and their parents. The goal was to see if using the app could help doctors better understand and support these children. About 200 children aged 8 to 20 and their parent…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New program aims to ease ICU recovery at home
Knowledge-focused CompletedThis pilot study tested a program called PICTURE-THIS, designed to help people who survived a stay in the intensive care unit (ICU) and their families transition back home. The program includes care coordination, check-ins over three months, and rehabilitation support. The study …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Exercise may sharpen aging brains after depression
Knowledge-focused CompletedThis study looked at whether aerobic exercise can improve thinking skills and brain structure in older adults who have recovered from late-life depression. Forty-six participants aged 60 and older completed supervised exercise sessions over 6 months. Researchers measured changes …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Can past stress block depression coping skills in teens?
Knowledge-focused CompletedThis study looked at how stressful childhood experiences affect the ability of teens aged 12-15 with depression symptoms to learn a coping skill called cognitive restructuring. The skill helps teens notice and challenge negative thoughts. Researchers measured skill learning and r…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Brain wave test may spot depression risk in teens
Knowledge-focused CompletedThis study looked at how the brain pays attention to negative images in teenage girls at risk for depression. Researchers used EEG to measure brain waves and tested if a type of feedback training could change attention patterns and reduce sad moods. The goal is to find new ways t…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Fitbits and smartphones could cut hospital readmissions after bladder cancer surgery
Knowledge-focused CompletedThis study tested whether using Fitbits and daily smartphone surveys after bladder cancer surgery can help doctors catch problems early and reduce hospital readmissions. 38 patients participated, with half receiving the remote monitoring program. The goal was to see if this appro…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Heart defects may leave lasting marks on the brain, new study shows
Knowledge-focused CompletedThis study looked at brain scans of 195 young adults (ages 18-30) with moderate to severe congenital heart disease to find signs of brain injury. The goal was to see if these brain changes could help predict memory or thinking problems later in life. No new treatments were tested…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Rural Kids' trauma care gets a teamwork boost
Knowledge-focused CompletedThis study looked at whether a special teamwork-focused training helps rural child advocacy centers better screen children for mental health problems after trauma. 147 staff members from these centers took part. The goal was to see if this approach makes it easier for centers to …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Can discord and videos help LGBTQ+ teens get mental health help?
Knowledge-focused CompletedThis study tested whether using online tools like videos and resources on Discord could help sexual and gender minority youth (ages 14-19) seek help for depression and anxiety. 81 participants joined groups on Discord with different combinations of tools for 4 weeks. The goal was…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Chemo's genetic impact on sperm revealed in new study
Knowledge-focused CompletedThis study looks at how chemotherapy changes sperm DNA in men with cancer. Researchers collect semen samples before treatment and one week after the first round of chemo. They compare the DNA and quality of the sperm to understand short-term effects. The goal is to learn more abo…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:53 UTC
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Can computer alerts help doctors avoid kidney damage from drugs?
Knowledge-focused CompletedThis study tested whether a computer system that alerts pharmacists about patients at risk for drug-related kidney injury can help doctors make safer medication decisions. The trial involved 698 hospitalized adults across eight hospitals. Pharmacists reviewed alerts and made reco…
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:08 UTC
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Can community programs improve health and cut costs for people with disabilities?
Knowledge-focused CompletedThis study looked at two community-based wellness programs for adults with disabilities like spina bifida, cerebral palsy, spinal cord injury, and traumatic brain injury. Researchers measured changes in health, mood, quality of life, and healthcare costs over up to 24 months. The…
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:29 UTC
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Brain study reveals how we adapt to noisy speech and accents
Knowledge-focused CompletedThis study looked at how the brain's temporal lobe processes speech in 48 people with epilepsy who were already undergoing brain monitoring for their condition. Participants listened to sounds with varying pitch and timing while their brain activity was recorded. The goal was to …
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:17 UTC