Heart defects may leave lasting marks on the brain, new study shows

NCT ID NCT05270356

Completed Knowledge-focused Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at brain scans of 195 young adults (ages 18-30) with moderate to severe congenital heart disease to find signs of brain injury. The goal was to see if these brain changes could help predict memory or thinking problems later in life. No new treatments were tested; instead, researchers gathered information to better understand the link between heart and brain health.

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Conditions

The condition(s) this trial relates to.

congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADULT CONGENITAL HEART DISEASE

Contacts and locations

Locations

Baylor College of Medicine

Houston, Texas, 77030, United States
Boston Children's Hospital

Boston, Massachusetts, 02115, United States
Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
Children's Hospital of Pittsburgh of UPMC

Pittsburgh, Pennsylvania, 15224, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Emory University

Atlanta, Georgia, 30322, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Indiana University

Indianapolis, Indiana, 46202-3082, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
University Health Network

Toronto, Ontario, ON M5G 2C4, Canada
University of Michigan

Ann Arbor, Michigan, 48103, United States
University of Utah

Salt Lake City, Utah, 84158, United States

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