Heart defects may leave hidden marks on the brain, new study shows

NCT ID NCT05270356

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 26 times

Summary

This study looked at brain scans of 195 young adults (ages 18-30) with moderate to severe congenital heart disease to find signs of hidden brain injury. Researchers used MRI to measure brain structure and damage that could lead to memory or thinking problems later in life. The goal was to learn more about how heart conditions affect the brain over time, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Hospital of Pittsburgh of UPMC

    Pittsburgh, Pennsylvania, 15224, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Indiana University

    Indianapolis, Indiana, 46202-3082, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • University Health Network

    Toronto, Ontario, ON M5G 2C4, Canada

  • University of Michigan

    Ann Arbor, Michigan, 48103, United States

  • University of Utah

    Salt Lake City, Utah, 84158, United States

Conditions

Explore the condition pages connected to this study.