Brain scans reveal why bladder control fails with age

NCT ID NCT04599088

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at how the brain controls the bladder in older women with urgency urinary incontinence. Researchers used MRI scans to compare brain activity during bladder filling and emptying in 207 women, both young and old, with and without incontinence. The goal was to understand why bladder control changes with age and find new ways to improve treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could point toward new targets for developing better treatments for age-related urinary incontinence.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may not apply to all people with incontinence.

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Conditions

The condition(s) this trial relates to.

overactive bladder Urinary Incontinence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213, United States

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