University Of Pittsburgh

This study aims to see if combining standard nurse counseling with a daily-use smartphone app is more effective at preventing relapse than counseling alone for men with alcohol use disorder. It will involve 74 male patients from a hospital in India who will be randomly assigned t…

This study aims to find out if people who survive a cardiac arrest outside the hospital recover better when transferred to a specialized cardiac arrest center versus staying at their local hospital. About 1,618 adult participants will be randomly assigned to receive either specia…

This study is testing whether a smartphone app that shows real-time blood sugar and activity data can help adolescents and young adults with type 2 diabetes better control their condition. For 90 days, participants will use the app along with a continuous glucose monitor and a Fi…

This study aims to find the best nap length for night shift workers to help control blood pressure and stay alert. Researchers will test five different nap durations (from 15 to 60 minutes) on 130 healthcare and public safety workers during simulated night shifts. The goal is to …

This study is testing a new approach to treat severe burns and traumatic skin injuries. Researchers want to see if taking a patient's own fat tissue and immediately placing it into the wound, along with a skin graft, leads to better healing than traditional methods. The goal is t…

This study is testing whether using a patient's own fat tissue during scar revision surgery can improve healing outcomes for people with severe burns or traumatic injuries. Researchers will compare this fat grafting approach to traditional skin grafting methods to see if it reduc…

This study is testing whether using a person's genetic test results to guide antidepressant prescriptions leads to better depression control. About 220 adults starting or adjusting their antidepressant medication will be randomly assigned to either receive this personalized, phar…

This study is creating and testing a new support program to help pregnant and postpartum people quit using tobacco and cannabis. Researchers will work with 25 participants to design activities that help them track their habits and manage mood. The goal is to help people quit duri…

This study tests whether adding sleep-focused treatments to standard depression care can quickly and lastingly reduce suicide risk in young adults. Researchers will compare three different sleep intervention approaches in 90 suicidal college students receiving outpatient treatmen…

This study is testing whether a new mobile phone app is practical and acceptable for helping people with schizophrenia or schizoaffective disorder take their medication as prescribed. The app will provide reminders, educational videos, and rewards to encourage adherence. Research…

This study is testing whether a video game called 'Singularities' can help reduce drinking and alcohol-related problems among teenagers. Researchers will compare it to another game about nutrition and wellness to see which is more effective. Nearly 2,000 teens aged 14-18 who have…

This study aims to prevent serious complications after major heart and vascular surgery in adults 65 and older. Researchers will test whether personalized pre-surgery training (including physical exercise, brain games, and social support) and special monitoring during surgery can…

This study aims to develop and test a practical plan to help outpatient clinics provide two key services to people who inject drugs: clean injection equipment and daily medication to prevent HIV (PrEP). Researchers will work with clinics, staff, and people with lived experience t…

This study aims to see if a 6-week sleep coaching program can help older adults with insomnia sleep better. It will involve 100 participants aged 60 and over who report poor sleep. The program teaches healthy sleep habits through in-person sessions and phone calls, avoiding the u…

This study aims to see if placing a thin layer of a patient's own fat tissue underneath a standard skin graft on the penis leads to better healing and results. It will involve 24 men who need reconstructive surgery due to injury, infection, or a condition called buried penis. Hal…

This study is testing whether a remote monitoring system using a Fitbit and weekly symptom surveys can help patients better manage side effects during cancer immunotherapy. Researchers want to see if this digital tool is easy for patients to use and if it improves their quality o…

This study aims to understand how a child's sensitivity to sounds, lights, and touch affects their sleep and emotions. Researchers will test a simple, parent-led bedtime routine involving gentle pressure massage and calming words to see if it helps autistic children aged 6-10 fal…

This small, early-stage study is testing whether a drug normally used for constipation (prucalopride) can help improve thinking, memory, and problem-solving skills in people with schizophrenia. Thirty-four stable patients will take the drug for four weeks alongside their regular …

This small pilot study will test a 6-month support program for children with type 1 diabetes who have 'hypoglycemia unawareness,' meaning they don't feel the usual warning signs of low blood sugar. The program combines child therapy, diet advice, and parent coaching. Researchers …

This study is testing a new behavioral skills program designed to help pregnant women with ADHD manage their symptoms during pregnancy and after giving birth. Researchers will compare the program to standard care in 80 participants to see if it's helpful and practical. The main g…

This study is exploring a new technology that aims to help people shift their mood. Researchers want to see if they can record brain activity from a person's 'good mood' day and then use that recording to help guide the person's brain back to that same state on a later 'bad mood'…

This study aims to understand the connection between thinking patterns, self-awareness of thoughts, and feelings of shame in adults who experience suicidal thoughts or have recently attempted suicide. Researchers will survey 220 adults in India to measure these factors. The goal …

This study aims to find the best ways to help teens and young adults with type 2 diabetes get support for basic needs like food, housing, and transportation. Researchers will test different approaches, including text message reminders and connections to community health workers, …

This study aims to learn if a highly sensitive blood test can detect tiny traces of cancer DNA in patients with early-stage triple negative breast cancer. Researchers will collect blood from 77 participants at diagnosis and during their treatment to see if the test can find cance…

This study aims to understand why some kidney transplants are rejected by the body's immune system. Researchers will collect and analyze kidney tissue and blood samples from 24 transplant patients over five years to create detailed maps of the cells involved in rejection. The goa…

This study is testing a web-based tool designed to help men make informed decisions about vasectomy and other birth control options. Researchers want to see if using the tool improves users' knowledge about the procedure and reduces their uncertainty about the decision. The study…

This study aims to understand how animal-based and plant-based protein shakes affect the body's metabolism and immune system signals. Healthy adults will drink three different high-protein smoothies on separate visits, and researchers will measure changes in their blood. The goal…