Can past stress block depression coping skills in teens?
NCT ID NCT04719897
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how stressful childhood experiences affect the ability of teens aged 12-15 with depression symptoms to learn a coping skill called cognitive restructuring. The skill helps teens notice and challenge negative thoughts. Researchers measured skill learning and retention over six months, along with stress responses. The goal is to understand how adversity impacts treatment success.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Repairing Thoughts cognitive restructuring module of FIRST cognitive behavioral therapy
What this could lead to
If successful, this study could help tailor depression treatments for teens based on their life experiences.
What could go wrong
This is an observational study with only 88 participants, so results may not apply to all teens. It does not test a new drug or cure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, 15213, United States