ADVERSE CHILDHOOD EXPERIENCES
Clinical trials for ADVERSE CHILDHOOD EXPERIENCES explained in plain language.
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Can a family advocate help break the cycle of trauma and addiction?
Prevention Recruiting nowThis study tests whether adding a trained family advocate to a proven parenting program can help prevent substance use and reduce childhood trauma. About 360 families from 36 high-risk communities in New Jersey will take part. The goal is to see if extra support makes the program…
Matched conditions: ADVERSE CHILDHOOD EXPERIENCES
Phase: NA • Sponsor: RTI International • Aim: Prevention
Last updated Jun 27, 2026 12:28 UTC
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New program aims to stop substance use before it starts in teens who've faced adversity
Prevention Recruiting nowThis study tests a program called GRIT, where community health workers coach teens (ages 11-14) and their families over six weekly sessions. The goal is to help teens who have experienced four or more adverse childhood events build self-regulation skills and avoid starting regula…
Matched conditions: ADVERSE CHILDHOOD EXPERIENCES
Phase: NA • Sponsor: University of California, Irvine • Aim: Prevention
Last updated Jun 27, 2026 11:03 UTC
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Can a simple program reduce toxic stress in kids?
Knowledge-focused Recruiting nowThis study tests a program that combines pediatrician counseling, community health workers, and parenting educators to help families with adverse childhood experiences (ACEs). Researchers will enroll 340 children aged 3-11 and follow them for a year to see if the program lowers s…
Matched conditions: ADVERSE CHILDHOOD EXPERIENCES
Phase: NA • Sponsor: Loma Linda University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Childhood trauma may rewire brain to crave nicotine
Knowledge-focused Recruiting nowThis study looks at how difficult childhood experiences might change brain function and make people more likely to start smoking. Researchers will give a small dose of nicotine or a placebo to 150 nonsmoking young adults aged 18-21, then use brain scans and questionnaires to meas…
Matched conditions: ADVERSE CHILDHOOD EXPERIENCES
Phase: EARLY_PHASE1 • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Breastfeeding and stress: new study seeks to help kids with sickle cell
Knowledge-focused Recruiting nowThis study looks at how early childhood experiences—like breastfeeding, stress, and social factors—affect children with sickle cell disease. Researchers will test a community-based breastfeeding support program for mothers and track health outcomes like asthma and chest pain epis…
Matched conditions: ADVERSE CHILDHOOD EXPERIENCES
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Can fixing sleep heal blood vessels after childhood trauma?
Knowledge-focused Recruiting nowThis study looks at how difficult childhood experiences and poor sleep might harm blood vessel function in young adults aged 18-29. Researchers will monitor sleep at home and test blood vessel health. Some participants will receive a 6-week sleep therapy program (CBT-i) to see if…
Matched conditions: ADVERSE CHILDHOOD EXPERIENCES
Phase: NA • Sponsor: Nathaniel Jenkins • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Nationwide study probes hidden mental health toll of school safety tactics
Knowledge-focused Recruiting nowThis study surveys 2,500 students and staff from schools that have and have not experienced a shooting. It aims to understand how school violence and safety strategies impact mental health, well-being, and educational outcomes. Participants self-report via questionnaires.
Matched conditions: ADVERSE CHILDHOOD EXPERIENCES
Sponsor: Teachers College, Columbia University • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:27 UTC