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New program aims to stop substance use before it starts in teens who've faced adversity

NCT ID NCT06821035

Recruiting now Prevention Sponsor: University of California, Irvine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called GRIT, where community health workers coach teens (ages 11-14) and their families over six weekly sessions. The goal is to help teens who have experienced four or more adverse childhood events build self-regulation skills and avoid starting regular alcohol or cannabis use. Half the families get the GRIT coaching; the other half receive a digital citizenship course. Researchers will follow both groups for a year to see which teens are less likely to start using substances.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
community health worker coaching with heart rate variability biofeedback
What this could lead to
If it works, this could provide a practical, non-drug way to help at-risk teens avoid early substance use and improve their long-term health.
What could go wrong
This is an early-stage study with 210 participants, so results may not apply to all teens. The intervention is time-intensive and relies on family engagement, which may limit real-world uptake.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVERSE CHILDHOOD EXPERIENCES FAMILY FUNCTIONING

Contacts and locations

Locations

  • The Regents of the University of California, Irvine

    RECRUITING

    Irvine, California, 92697-7600, United States

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