Exercise may sharpen aging brains after depression

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Men and women 60+ years 2. Major Depressive Episode in older adulthood (since age 55) 3. Current level of depressive symptoms does not meet criteria for a Major Depressive Episode 4. Ambulatory without pain or the assistance of walking devices 5. Able to speak and read English 6. Exercise level of \<100 minutes per week on average 7. Medical clearance by primary care physician (PCP) 8. Living in community for duration of the study 9. Reliable means of transportation 10. No diagnosis of a neurological disease 11. Eligible to undergo MRI Exclusion Criteria: 1. Current diagnosis of a Major Depressive Episode 2. Psychosis 3. Significant suicide risk (i.e., current, active suicidal ideation with a plan) 4. Electroconvulsive therapy within the past 12 months 5. Engaging in moderate-intensity exercise \>100 minutes per week on average 6. Current treatment for cancer - except non-melanoma skin 7. Neurological condition (MS, Parkinson's, Dementia, MCI) or brain injury (Stroke) 8. Substance Use disorder in the past 3-months 9. Current treatment for congestive heart failure, angina, uncontrolled arrhythmia, deep vein thromboses (DVT) or other cardiovascular event 10. Myocardial infarction, coronary artery bypass grafting, angioplasty or other cardiac condition in the past year including uncontrolled hypertension 11. Regular use of an assisted walking device 12. Presence of metal implants (pacemaker, stents) that would be MR ineligible 13. Claustrophobia 14. Color Blindness 15. Significant visual or hearing impairments that would preclude neuropsychological assessment or communication with study staff via a virtual format (videoteleconference) 16. Not fluent in English 17. Not medically cleared by PCP 18. Traveling consecutively for 3+ weeks during the study 19. MOCA (\<20 to exclude) and MADRS (\>9 to exclude)