Sun Yat-sen University

This study tests a new drug combination (goselasib plus other treatments) as a first-line therapy for people with a specific genetic mutation (KRAS G12C) in advanced or metastatic non-small cell lung cancer. About 69 adults who have not had prior treatment for their advanced canc…

This study tests whether combining two drugs (hetrombopag and rhTPO) works better than hetrombopag alone to raise dangerously low platelet counts caused by cancer treatments like chemotherapy. About 204 adults with solid tumors and severe low platelets will be randomly assigned t…

This early-phase study tests a personalized cell therapy (TCR-T) in 25 adults with advanced solid tumors caused by KRAS mutations, such as certain colorectal and lung cancers. The treatment involves collecting the patient's own immune cells, engineering them to better recognize a…

This study tests a new approach for people with early-stage lung cancer who cannot or do not want chemotherapy. Before surgery, patients receive a short course of focused radiation (SBRT), an immunotherapy drug (tislelizumab), and an antiangiogenic drug (anlotinib) to shrink the …

This phase 2 trial tests whether adding trilaciclib to the chemotherapy drug eribulin can protect bone marrow in people with advanced triple-negative breast cancer who have already tried at least two prior chemotherapies. The study will measure how well the combo reduces severe l…

This study looks at 120 people with advanced liver cancer caused by hepatitis B who are also getting immunotherapy. It compares two antiviral drug plans: one using TAF alone, and the other using TAF plus ETV. The goal is to see which plan helps people live longer and better contr…

This study looks at whether giving radiation therapy after surgery can help prevent adrenal cancer from coming back in people with high-risk disease. About 58 adults who had their cancer fully removed will be randomly assigned to either receive radiation or just be watched. The m…

This study tests whether adding lubiprostone, a drug used for constipation, to standard maintenance therapy can delay cancer recurrence in adults with colorectal cancer that has spread to the lining of the abdomen. About 124 participants who have had surgery to remove visible can…

This study tests whether a combination of three drugs (disitamab vedotin, tunlametinib, and a PD-1 antibody) can shrink tumors in people with advanced HER2-positive gastric cancer who have already tried at least two other treatments. About 76 adults will receive the drugs intrave…

This study tests whether adding the arthritis drug celecoxib to standard chemotherapy (R-CHOP) works better than chemotherapy alone for people with a rare, aggressive form of lymphoma called CD5-positive diffuse large B-cell lymphoma. About 60 adults with newly diagnosed advanced…

This study tests whether combining two drugs, scipibaimab and tislelizumab, can shrink tumors in people with advanced nasopharyngeal cancer that has returned or spread and no longer responds to first-line chemotherapy. About 37 adults aged 18-75 will receive the combination. The …

This study tests a new flexible sheath (ArcFlex) used during TAVR, a procedure to replace a diseased aortic heart valve without open-heart surgery. The sheath helps guide the new valve into place, and researchers want to see if it improves success rates and safety. About 180 peop…

This study is testing a virtual companion that talks with teenagers to help them cope with stressful life events. About 35 teens aged 14 to 25 will use the program for 4 weeks. The goal is to see if it reduces emotional symptoms and improves resilience and coping skills.

This study will develop an artificial intelligence (AI) model to predict how well patients with a rare type of lymphoma (NK/T-cell lymphoma) respond to their first chemotherapy. Researchers will use medical images and tissue samples from 100 patients to train the AI. The goal is …

This study looks at how the amount and type of carbohydrates in your diet affect blood sugar, cholesterol, and gut bacteria. Researchers will give 20 adults with or at risk for metabolic syndrome different carb diets and measure changes. The goal is to understand how carbs impact…

This study tests a 4-week online program designed to help parents of children aged 3-6 support healthy behaviors like physical activity, less screen time, handwashing, and reducing sugary drinks. Researchers will compare parents who get the program right away to those on a waitli…