Could less be more? shorter immunotherapy course tested for head and neck cancer

NCT ID NCT07373990

First seen Feb 01, 2026 · Last updated May 16, 2026 · Updated 14 times

Summary

This study compares a shorter versus longer course of the immunotherapy drug tislelizumab, given alongside standard chemoradiotherapy, for people with advanced nasopharyngeal cancer. About 418 adults aged 18 to 65 with stage T4N1 or T1-4N2-3 disease will be randomly assigned to receive either 6 or 8 total doses of tislelizumab. The goal is to see if the shorter course is just as effective at preventing cancer from returning or spreading, while potentially reducing side effects and treatment burden.

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