Sun Yat-sen University

This study tested a combination of an immunotherapy drug (anti-PD-1) and a chemotherapy drug (albumin-bound paclitaxel) in 27 people whose cervical cancer had returned or worsened after standard treatment. The goal was to see if the combination could shrink tumors and help patien…

This study tested whether adding a low-dose chemotherapy drug (capecitabine) to standard hormone therapy (aromatase inhibitor) works better than hormone therapy alone for women with a common type of advanced breast cancer (HR+/HER2-). The trial involved 263 women who had not yet …

This study looked at whether adding chemotherapy to radiation therapy is necessary for people with intermediate-risk nasopharyngeal cancer when using modern radiation techniques (IMRT). The trial included 338 participants and compared the standard treatment (chemoradiotherapy) to…

This study looked at 200 people with advanced liver cancer whose first treatment (bevacizumab plus sintilimab) stopped working. Researchers compared two second-line options: a PD-1 inhibitor combined with either lenvatinib or regorafenib. The goal was to see which combination wor…

This study tested whether adding oral diabetes drugs (metformin/pioglitazone or sitagliptin) to a short-term insulin pump can improve long-term blood sugar control in people newly diagnosed with type 2 diabetes. 264 participants were followed for one year to see how many could ac…

This study tested whether adding bevacizumab to a three-drug chemotherapy (FOLFOXIRI) could shrink liver tumors enough to allow surgery in people with a specific genetic type (RAS mutation) of colorectal cancer that had spread only to the liver. 138 adults with initially inoperab…

This study tested whether giving a combination of two drugs (cadonilimab and lenvatinib) before surgery could shrink kidney tumors in 39 patients with kidney cancer. The goal was to make it safer to remove only the tumor and save the rest of the kidney, especially for patients wh…

This early-phase study tested a new dosing schedule of cetuximab combined with capecitabine as maintenance therapy for people with a specific type of metastatic colorectal cancer (KRAS/BRAF wild-type). The study involved 24 participants and aimed to find the safest dose and under…

This study tested whether adding the antibiotic moxifloxacin to standard chemotherapy improves outcomes for people with operable breast cancer. 559 participants were randomly assigned to receive either moxifloxacin or a placebo alongside their chemo. The main goal was to see if t…

This study tested a combination of two drugs, apatinib and etoposide, in 35 women with ovarian cancer that had stopped responding to platinum-based chemotherapy. The goal was to see if the combination could shrink tumors or slow disease progression. Participants took the drugs by…

This study tested a powerful three-drug combination in 46 people with a specific type of lung cancer (EGFR-mutated) that had spread to the lining of the brain and spinal cord (meningeal metastasis). The treatment used a high dose of the targeted pill furmonertinib, plus the IV dr…

This study tested whether taking anlotinib pills after initial chemotherapy can help keep advanced soft tissue sarcoma from growing. 49 adults with certain types of sarcoma took anlotinib daily. The goal was to see how long the cancer stayed stable and to check safety. Anlotinib …

This study tested a combination of two drugs, cadonilimab and regorafenib, in 36 adults with advanced liver cancer that had worsened after standard therapy. The goal was to see if the combination could control the cancer longer. Participants received both drugs orally or by infus…

This study looked at 96 people with advanced bile duct cancer that couldn't be removed by surgery. Researchers wanted to see if adding a liver-directed chemotherapy (HAIC) to a standard drug mix (Gemox, lenvatinib, and toripalimab) could help patients live longer without the canc…

This study tested whether adding an extra chemotherapy drug (capecitabine) after standard treatment helps people with advanced nasopharyngeal cancer that is likely to spread. 294 patients received either standard chemoradiotherapy alone or standard treatment plus capecitabine. Th…

This study tested a combination of an immunotherapy drug (durvalumab) and chemotherapy delivered directly to the liver (HAIC) in 30 adults with advanced liver cancer that had spread into the main portal vein. The goal was to see if the combination could improve one-year survival.…

This study reviewed medical records of 300 adults with high-risk liver cancer who received a combination of two drugs (atezolizumab and bevacizumab) plus chemotherapy directly into the liver artery. The goal was to see how well this treatment worked and how safe it was in real-wo…

This study tested a combination of two targeted drugs, pamiparib and surufatinib, in 29 women with ovarian cancer that had stopped responding to platinum chemotherapy and PARP inhibitors. The goal was to see if the combo could shrink tumors or slow cancer growth. This is not a cu…

This study looked at 74 people with liver cancer whose tumors shrank completely after non-surgical treatments like chemoembolization, targeted therapy, and immunotherapy. The goal was to see if having surgery to remove any remaining tumor is better than simply watching and waitin…

This study tested a new surgical technique for esophageal cancer that avoids a large chest incision. 35 patients with early-stage cancer received this less invasive procedure. The goal was to see if it could lower complication rates while still effectively removing the cancer. Re…

This study tested an artificial intelligence platform that screens for cognitive problems like dementia by analyzing how people move their eyes. Over 1,500 participants with various cognitive conditions took part. The goal was to see if eye movement patterns could accurately dete…

This study tested a new way to find small cancer spots in neck lymph nodes of people with nasopharyngeal cancer. Researchers combined MRI scans with a special ultrasound that uses a contrast agent. They aimed to create a better rule for spotting these tiny metastases. 348 patient…

This study looked at two ways of giving pain medicine through an epidural after lung surgery: a steady drip versus small, timed bursts. The goal was to see which method helps patients recover better. 252 adults having lung surgery took part, and researchers measured their recover…

This study tested whether ulinastatin, a drug that blocks certain enzymes, can lower the chance of severe mouth sores in people with advanced nasopharyngeal cancer receiving chemotherapy and radiation. 179 participants were randomly assigned to receive either standard care plus u…

This study tested a computer program that acts like a friendly peer to help teenagers deal with stressful life events. 55 teens aged 14-25 chatted with the virtual agent over 4 weeks. The goal was to see if it could improve their mood, resilience, and ability to handle stress. Th…

This study tested whether neurotropin, a drug that may protect nerves, can reduce the nerve damage caused by oxaliplatin chemotherapy in people with stage II or III colorectal cancer. The trial included 333 participants who had surgery and were about to start chemotherapy. Resear…

This study tested two different sonic toothbrushes against a standard manual toothbrush to see which one reduces surface stains on teeth better. Over 8 weeks, 129 adults brushed as usual and had their stains measured. The goal was to find out if the sonic brushes lead to noticeab…

This study followed over 1,100 pregnant women in Guangzhou to see how their diet and nutrition during and after pregnancy related to blood sugar problems and their children's growth, development, and allergies up to age 5. Researchers measured blood sugar and insulin levels durin…

This study tested whether a new type of PET scan (FAPI-PET/CT) can accurately tell if rectal cancer has been completely eliminated after chemoradiotherapy. Fifty-two adults with locally advanced rectal cancer received the scan before surgery. The goal was to see if the scan could…

This study looked at whether watching Mukbang videos (videos of people eating large amounts of food) affects appetite in children with cancer who are in the hospital for radiation or chemotherapy. Researchers tracked 179 children's viewing habits and appetite over time. The goal …

This study looked at 103 research articles to compare the nutrients in breast milk from mothers who gave birth early (preterm) versus full-term. The goal was to see if there are differences in energy, protein, fat, and other components. This is a knowledge-gathering study, not a …

This study looked at whether low oxygen levels after esophageal cancer surgery increase the chance of a leak where the esophagus is reconnected. Researchers reviewed records of 2,083 patients, comparing those with low oxygen to those with normal levels. The goal was to see if cor…

This study used artificial intelligence to analyze data from 7,000 people with liver cancer. The goal was to create a tool that helps doctors predict liver function, treatment outcomes, and cancer spread. The tool is designed to guide decisions about surgery, chemotherapy, and ot…