New combo therapy shows promise for tough-to-treat liver cancer

NCT ID NCT04945720

First seen Feb 28, 2026 · Last updated Jun 10, 2026 · Updated 18 times

Summary

This study tested a combination of an immunotherapy drug (durvalumab) and chemotherapy delivered directly to the liver (HAIC) in 30 adults with advanced liver cancer that had spread into the main portal vein. The goal was to see if the combination could improve one-year survival. Participants received the treatment as an open-label, single-arm regimen. The study is completed, and results will help determine if this approach is safe and effective for this difficult-to-treat condition.

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Contacts and locations

Locations

  • Department of Minimally Invasive and Interventional Radiology, Liver Cancer Study and Service Group, Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 500060, China

Conditions

Explore the condition pages connected to this study.