New combo therapy shows promise for Tough-to-Treat lung cancer brain spread

This study tested a combination of three drugs—high-dose furmonertinib, bevacizumab, and chemotherapy injected into the spine—in 46 people with a specific type of lung cancer (EGFR-mutated) that had spread to the lining of the brain and spinal cord. The goal was to see if this treatment could control the cancer in the brain and body. Participants had to have certain EGFR mutations and confirmed spread to the brain lining. The study is now complete, and results will help doctors understand if this approach is safe and effective for this serious condition.