New combo therapy for lung cancer under Real-World watch

NCT ID NCT07563205

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study follows 100 adults with metastatic non-small cell lung cancer who have certain EGFR gene mutations and are receiving amivantamab plus platinum-based chemotherapy through an early access program. Researchers will collect medical data to see how long the treatment keeps the cancer from progressing. No extra tests are needed—just routine care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
amivantamab plus platinum-based chemotherapy
What this could lead to
If successful, this study could show that combining amivantamab with chemotherapy helps control metastatic lung cancer longer in people with specific EGFR mutations.
What could go wrong
This is an observational study, not a controlled trial, so results may be less reliable. It is also small (100 people) and only follows participants for about 1.5 years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHP Hôpital Avicennes

    RECRUITING

    Bobigny, 93000, France

    Contact Email: •••••@•••••

  • CH de la Région d'Annecy - Service de Pneumologie

    RECRUITING

    Pringy, 74374, France

    Contact Email: •••••@•••••

  • CH du Pays d Aix - Service des Maladies Respiratoires

    RECRUITING

    Aix-en-Provence, 13616, France

    Contact Email: •••••@•••••

  • CHRU de Nancy

    ACTIVE_NOT_RECRUITING

    Nancy, 54000, France

  • CHU La Réunion Site Sud

    RECRUITING

    Saint-Pierre, 97410, France

    Contact Email: •••••@•••••

  • Centre Antoine Lacassagne

    ACTIVE_NOT_RECRUITING

    Nice, 06149, France

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69373, France

    Contact Email: •••••@•••••

  • Hôpital A. Mignot

    RECRUITING

    Le Chesnay, 78157, France

    Contact Email: •••••@•••••

  • Hôpital Louis Pradel

    ACTIVE_NOT_RECRUITING

    Bron, 69500, France

  • Hôpital Nord

    RECRUITING

    Marseille, 13915, France

    Contact Email: •••••@•••••

  • Institut Curie

    ACTIVE_NOT_RECRUITING

    Paris, 75005, France

  • Pneumologie CHU St Etienne

    RECRUITING

    Saint-Etienne, 42270, France

    Contact Email: •••••@•••••

  • Pneumologie Centre François Baclesse

    ACTIVE_NOT_RECRUITING

    Caen, 14000, France

  • Pneumologie Centre Hospitalier Intercommunal de Créteil

    RECRUITING

    Créteil, 94010, France

    Contact Email: •••••@•••••

  • Pneumologie Hôpital Calmette

    RECRUITING

    Lille, 59000, France

    Contact Email: •••••@•••••

  • Pneumologie Hôpital privé Jean Mermoz

    RECRUITING

    Lyon, 69085, France

    Contact Email: •••••@•••••

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