Can a common gut drug keep colorectal cancer at bay?

This study tests whether adding lubiprostone, a drug used for constipation, to standard maintenance therapy can delay cancer recurrence in 124 adults with colorectal cancer that has spread to the lining of the abdomen. Participants have already had surgery to remove visible tumors and may have received heated chemotherapy inside the abdomen. The goal is to see if the combination improves the chance of staying cancer-free for at least one year compared to maintenance therapy alone.