New hope for hard-to-treat head and neck cancer: drug combo before surgery shows promise
NCT ID NCT07589049
First seen May 18, 2026 · Last updated Jun 14, 2026 · Updated 4 times
Summary
This study tests whether giving two drugs (becotatug vedotin and pucotenlimab) before surgery can shrink tumors in people with recurrent head and neck cancer that has stopped responding to standard treatments. About 42 adults with EGFR-positive cancer will receive 3 cycles of the drug combo, then surgery, followed by more therapy. The main goal is to see how many patients have a major reduction in tumor cells after the drugs.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEAD AND NECK SQUAMOUS CELL CARCINOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Affiliated Hospital of Guangdong Medical University
Zhanjiang, Guangdong, China
-
Cancer Hospital of Guangzhou Medical University
Guangzhou, Guangdong, China
-
Cancer Hospital of Shantou University Medical College
Shantou, Guangdong, China
-
Ganzhou Cancer Hospital
Ganzhou, Jiangxi, China
-
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China
-
Guangzhou First People's Hospital
Guangzhou, Guangdong, China
-
Qingyuan People's Hospital
Qingyuan, Guangdong, China
-
Shenzhen Second People's Hospital
Shenzhen, Guangdong, China
-
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China
-
The First People's Hospital of Foshan
Foshan, Guangdong, China
-
The Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
-
Zhujiang Hospital of Southern Medical University
Guangzhou, Guangdong, China
Conditions
Explore the condition pages connected to this study.