Alexandria University
Clinical trials sponsored by Alexandria University, explained in plain language.
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New study tests magnetic mallet vs piezotome for easier dental implants
Disease control CompletedThis study looked at 20 people with a narrow upper jawbone who needed dental implants. It compared two tools—a magnetic mallet and a piezotome—to widen the bone and place implants and bone graft at the same time. The goal was to see which tool gives better implant stability and l…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Which crown wins for Kids' teeth? new study compares bioflex, zirconia, and stainless steel
Disease control CompletedThis study tested three types of dental crowns—bioflex, zirconia, and stainless steel—on 45 children aged 6 to 8 with badly decayed baby molars. The goal was to see which crown keeps gums healthiest and lasts best. Each child got one crown type, and researchers checked gum health…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New dental implant technique aims to save bone and gum shape
Disease control CompletedThis study tested two methods of using a collagen membrane during immediate dental implant placement in people with a damaged front tooth. The goal was to see which method better preserves the bone and gum around the implant. Eighteen adults with a single upper tooth needing extr…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New 3D mesh could improve surgery for broken bones around the eye
Disease control CompletedThis study tested a new 3D-printed mesh for repairing complex fractures around the eye socket and cheekbone. Twenty-four adults with these fractures received either the new mesh or standard metal plates and screws. The goal was to see if the new mesh led to better bone alignment …
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New flexible crowns put to the test in Kids' cavity repair
Disease control CompletedThis study tested whether BioFlex crowns work as well as standard stainless steel crowns for fixing cavities in children's back baby teeth. 74 children received one of each crown type and were checked over 12 months. Researchers looked at how well the crowns held up, whether they…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Plastic vs. titanium: which jaw implant heals better?
Disease control CompletedThis study tested whether custom-made 3D-printed plastic (PEEK) plates are better than standard titanium plates for repairing a broken jawbone near the back of the mouth. Eighteen adults with a recent jaw fracture received one of the two plate types during surgery. The researcher…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Natural mouthwashes take on cavity germs in kids
Disease control CompletedThis study tested whether natural mouthwashes made from ozonated olive oil or propolis can fight cavity-causing bacteria as well as the standard chlorhexidine mouthwash. Fifty-one children at high risk for cavities used one of the three mouthwashes. Researchers measured changes i…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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Fish oil and aspirin may boost gum treatment in smokers
Disease control CompletedThis study tested whether taking omega-3 supplements and low-dose aspirin, with or without doxycycline, can improve standard gum treatment for smokers with advanced gum disease (stage III periodontitis). 45 smokers participated. The goal was to see if these add-on therapies reduc…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 05, 2026 11:55 UTC
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New study tests better membranes for dental implants in weak jawbones
Disease control CompletedThis study tested two types of platelet-rich fibrin (PRF) membranes used with bone graft to support dental implants in people with a thin lower jaw. Twenty adults with missing back teeth and a narrow jawbone received implants along with either a standard PRF or an extended PRF me…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated May 04, 2026 16:17 UTC
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New jaw surgery shows promise for cleft patients
Disease control CompletedThis study tested a modified jaw surgery (Le Fort I osteotomy) in 9 adults with cleft lip and palate who also had a misaligned bite and a bone gap in the upper jaw. The surgery aimed to improve facial profile and close the bone gap. Researchers measured changes in the bone defect…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Tiny screws vs. screws & pokes: which better widens adult jaws?
Disease control CompletedThis study tested two dental procedures to correct a narrow upper jaw in adults. Researchers compared using small screws alone to using screws combined with tiny punctures in the palate bone. They measured which method created more skeletal expansion and less tooth tipping after …
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated Apr 15, 2026 16:14 UTC
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Sugar-Free wipes may keep baby teeth Cavity-Free
Prevention CompletedThis study tested whether cleaning babies' teeth and gums with special xylitol wipes could lower the bacteria that cause cavities. Twenty healthy children aged 9 to 18 months used the wipes three times a day for four weeks. Researchers measured bacteria and acid levels in their s…
Phase: NA • Sponsor: Alexandria University • Aim: Prevention
Last updated May 17, 2026 03:15 UTC
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Which pain block works best for kids? new study compares two techniques
Symptom relief CompletedThis study looked at 60 children aged 2 to 7 having lower abdominal surgery to see which pain block works better: an erector spinae block or a caudal block. Both are numbing injections given before surgery to reduce pain. The researchers measured pain using a special scale and tr…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 17, 2026 03:16 UTC
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New dental implant surface may speed up tooth replacement
Symptom relief CompletedThis study looked at whether dental implants with a calcium titanate surface can be loaded (fitted with a crown) earlier than usual. Twenty-two adults with good jawbone received implants in the lower back jaw. Researchers measured implant stability and bone changes over time to s…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 17, 2026 03:14 UTC
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Insulin ointment may speed healing of blistering skin disease
Symptom relief CompletedThis study tested whether applying insulin directly to skin sores helps them heal faster in people with pemphigus vulgaris, a rare autoimmune blistering disease. Twenty patients each had three similar sores treated with either long-acting insulin, short-acting insulin, or a saltw…
Phase: PHASE2 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 17, 2026 03:12 UTC
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New jaw surgery technique may reduce nerve damage risk
Symptom relief CompletedThis study compared two surgical methods to fix a specific type of jaw fracture (subcondylar fracture) in 20 patients. One method aims to reduce the risk of facial nerve injury and other complications. The goal was to see which approach leads to better recovery, less pain, and hi…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 17, 2026 03:11 UTC
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New nerve block eases chronic back pain in small study
Symptom relief CompletedThis study tested a nerve block injection (erector spinae plane block) to relieve chronic low back pain caused by degenerative disc disease. 40 adults aged 30-65 with moderate to severe pain that didn't improve with other treatments received the injection. The goal was to reduce …
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 17, 2026 03:10 UTC
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Ozone and platelet injection eases jaw pain in small trial
Symptom relief CompletedThis study tested a procedure called arthrocentesis (joint washing) for people with a displaced jaw disc that causes pain and limited mouth opening. One group received ozonated water alone, while the other also got a platelet-rich plasma (PRP) injection. The goal was to see which…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 17, 2026 03:08 UTC
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Virtual reality calms heart patients better than relaxation exercises?
Symptom relief CompletedThis study tested two simple, drug-free methods to help heart patients in the cardiac care unit feel less anxious and more focused. One group used virtual reality (VR) headsets, while the other group practiced a muscle relaxation technique. Researchers measured changes in anxiety…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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New pain block combo eases drain discomfort after heart surgery
Symptom relief CompletedThis study tested whether adding two extra nerve blocks to a standard one can better control pain from chest drains after heart surgery. 180 adults having planned heart surgery through the breastbone took part. The goal was to see if these extra blocks reduce pain at the drain si…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Gadgets ease dental pain for kids with ADHD
Symptom relief CompletedThis study tested if using technology-based distractions (like watching videos or playing games) can reduce pain and anxiety for children with ADHD during dental procedures. 48 children participated, and researchers measured their pain through behavior, heart rate, and self-repor…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Magnesium boosts pain relief after sleeve gastrectomy, study finds
Symptom relief CompletedThis study tested whether adding magnesium sulfate to the local anesthetic bupivacaine improves pain control after laparoscopic sleeve gastrectomy (weight-loss surgery). Sixty-eight adults aged 18-50 with a BMI of 30-50 participated. The results showed that adding magnesium prolo…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Laser light eases pain after Kids' tooth pulls, study finds
Symptom relief CompletedThis study tested whether a low-level laser can help children aged 5 to 8 heal better and feel less pain after having a baby molar removed. Each child had two teeth pulled—one side got laser treatment, the other did not. The researchers measured healing and pain using photos and …
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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Tea tree oil may help heal burns faster, small study finds
Symptom relief CompletedThis study tested whether tea tree oil dressings help second-degree burns heal better than standard dressings. Thirty patients with recent burns covering up to 10% of their body took part. Researchers checked wound healing and signs of infection over 10 days in the hospital.
Phase: EARLY_PHASE1 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 11, 2026 20:51 UTC
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Ozone shots for jaw pain: which strength works best?
Symptom relief CompletedThis study tested different strengths of ozone gas injected into the jaw joint to treat TMJ disorder. Twenty adults with jaw clicking, popping, or limited mouth opening who had not improved with other treatments took part. The goal was to see which ozone concentration best reduce…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 11, 2026 20:48 UTC
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Licorice or laser: which fades dark gums better?
Symptom relief CompletedThis study tested two treatments for dark gums: a licorice extract gel and a special laser. Twenty-six healthy adults with dark spots on their front gums were treated and followed for 36 weeks. The goal was to see which method worked better at lightening the gums and how satisfie…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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Laser wisdom tooth removal may reduce pain and swelling
Symptom relief CompletedThis study tested whether using an Er:YAG laser to remove impacted wisdom teeth is better than the usual surgical method. Twenty-four healthy adults aged 20-30 took part. The researchers measured pain, swelling, and how well the jaw could open after surgery to see if the laser le…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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Ozone or platelet gel: which heals gum wounds better?
Symptom relief CompletedThis study tested two topical treatments—ozonated gel and titanium platelet-rich fibrin (TPRF)—on 39 adults to see which helps palatal wounds heal faster and with less pain after gum graft surgery. Participants rated their pain and had wound photos taken over 14 days. The goal wa…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 11, 2026 20:41 UTC
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New pump technique for jaw pain shows promise in small trial
Symptom relief CompletedThis study tested a new way to perform a jaw joint washout (arthrocentesis) for people with a painful TMJ disorder called internal derangement. Thirty adults received either the new method using a dental implant motor pump or the standard manual technique. Researchers measured ch…
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 11, 2026 20:40 UTC
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Can a common drug reverse Poison-Induced delirium? new study says yes
Symptom relief CompletedThis study tested the drug rivastigmine in 100 adults with delirium caused by poisoning from drugs like clozapine or antidepressants. The goal was to see if it could safely restore consciousness and calmness. Results showed improvement in consciousness levels, offering a potentia…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 06, 2026 16:13 UTC
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Green dialysis: less fluid, same results?
Knowledge-focused CompletedThis study looked at whether lowering the dialysate flow rate (the fluid used in dialysis) from 500 to 300 ml/min still cleans the blood properly in people with end-stage kidney disease. 80 adults on regular dialysis tried both flow rates for a week each. Researchers measured how…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 17, 2026 03:18 UTC
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Pharmacists cut medication errors in hospital transfers
Knowledge-focused CompletedThis study tested whether having a clinical pharmacist review medications when patients move to the intensive care unit reduces errors. Researchers tracked 126 patients transferred within Alexandria Main University Hospital. They compared prescriptions checked by pharmacists vers…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 17, 2026 03:17 UTC
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Vaping lung damage: new study reveals best ways to diagnose it
Knowledge-focused CompletedThis study looked at 60 adults with vaping-related lung injury to see how well chest CT scans, ultrasound, and a lung fluid test (bronchoalveolar lavage) can diagnose the condition. The goal was to understand which tests work best and how they relate to hospital stay, ICU need, a…
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 17, 2026 03:17 UTC
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ER study reveals widespread Long-Term painkiller use
Knowledge-focused CompletedThis study looked at 350 adults visiting the emergency room at Alexandria Main University Hospital to see how many were regularly using NSAIDs (pain relievers like ibuprofen or naproxen). The goal was to find out how common long-term use is and whether patients know about the pos…
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 17, 2026 03:16 UTC
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AI boosts Nurses' heart test skills in new study
Knowledge-focused CompletedThis study tested a new training program that uses artificial intelligence to create realistic heart test scenarios for nurses. 64 nurses participated to see if the AI-based training improved their knowledge, decision-making, and confidence in reading ECGs. The goal was to find b…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 17, 2026 03:14 UTC
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Nurse phone distraction linked to 105 clinical incidents
Knowledge-focused CompletedThis study looked at how nurses use smartphones during work and how it impacts patient safety. Researchers surveyed 368 nurses in Egypt and found 105 clinical incidents linked to phone distraction. The study also collected nurses' ideas for safely using phones in hospitals.
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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3D printed guides promise precision in jaw surgery
Knowledge-focused CompletedThis study tested how accurate 3D printed surgical guides are for repairing broken jawbones. Twenty-four adults with a single-sided jaw fracture received surgery using one of two virtual planning methods. The main goal was to measure how precisely the bone pieces were realigned b…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Tailored 3D-Printed implants tested for broken jaw surgery
Knowledge-focused CompletedThis study tested whether custom-made surgical stents and plates can help doctors more accurately fix broken jaw bones. Seven patients with a specific type of jaw fracture received the personalized implants. Researchers compared CT scans before and after surgery to see how well t…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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AI tutor boosts nursing Students' brainpower and bedside manner
Knowledge-focused CompletedThis study tested whether an AI-powered learning platform could improve reflective thinking, emotional skills, and clinical learning in 140 nursing students. Participants were students in psychiatric mental health clinical rotations. The study compared the AI platform to standard…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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AI boosts nurse drug calculations in new study
Knowledge-focused CompletedThis study tested whether an AI-powered mobile app helps nurses improve their drug calculation skills compared to traditional classroom training. Fifty-six nurses from various hospital units participated. The goal was to see if the AI approach leads to better knowledge, decision-…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Can a special program teach teens to avoid drugs and alcohol?
Knowledge-focused CompletedThis study tested an educational program designed to improve teenagers' knowledge and behavior around substance abuse. 226 adolescents aged 10-18 took part. The program used a behavior change model to help teens understand the risks and make healthier choices.
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC
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Sarcoidosis drugs under scrutiny: do they trigger cancer?
Knowledge-focused CompletedThis study followed 40 adults with lung sarcoidosis who were taking or about to start immunosuppressive therapy. Researchers checked for new lymphoma cases over 12 months using lymph node biopsies. The goal was to see if these medications increase cancer risk.
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Which side is better for Ultrasound-Guided central line placement?
Knowledge-focused CompletedThis study tested whether placing a central line (a tube for long-term medicine) through the left or right armpit area works better. 80 patients who needed a port-a-cath were included. Doctors used ultrasound to guide the needle and checked success with X-ray. The goal was to fin…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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Sleep apnea may raise risk of repeat blood clots in the lungs
Knowledge-focused CompletedThis study looked at 40 adults who had a pulmonary embolism (a blood clot in the lungs) to see if those with sleep-disordered breathing had worse short-term outcomes or a higher chance of the clot coming back within a year. Participants were monitored for one year, and recurrence…
Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Gum disease and obesity: new clues from a hormone in your gums
Knowledge-focused CompletedThis study looked at levels of a hormone called prolactin in the gum fluid of 26 people who have both obesity and gum disease (stage II or III). Researchers measured prolactin before and after a standard deep-cleaning treatment to see if the hormone levels changed. The goal was t…
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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Computer-Aided jaw surgery shows promise in small trial
Knowledge-focused CompletedThis study tested whether using computer planning and custom-made plates could improve jaw bone reconstruction after tumor surgery. Thirty people with non-cancerous jaw tumors took part. The approach aimed to make surgery more accurate and improve healing and appearance. Results …
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 07, 2026 18:43 UTC
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Researchers hunt for clues to better back pain shots
Knowledge-focused CompletedThis study looked at 100 adults with sacroiliac joint pain to find out which patient traits predict better results from ultrasound-guided injections of numbing medicine and steroids. Researchers measured pain and disability before and after the shot. The goal was to help doctors …
Phase: NA • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 07, 2026 18:43 UTC
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Fast-Track hip surgery may cut death risk, study finds
Knowledge-focused CompletedThis study looked at whether performing hip fracture surgery within 48 hours lowers the risk of death and other complications. Researchers followed 150 patients aged 50 and older for 30 days after surgery. They measured death rates, blood clots, confusion after surgery, and how l…
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Knowledge-focused
Last updated May 07, 2026 18:41 UTC