Blood test and CT combo may spare rectal cancer patients a second surgery
NCT ID NCT07722533
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This study tests whether a combination of serial C-reactive protein blood tests and targeted CT scans can safely identify which rectal cancer patients can skip a temporary ileostomy after laparoscopic low anterior resection. Anastomotic leakage is a serious complication, and a protective ileostomy reduces its impact but comes with its own risks. The trial will follow 60 adults undergoing elective surgery, measuring CRP daily and performing CT when criteria are met, to see if the surveillance pathway can avoid unnecessary ileostomies without increasing dangerous leaks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Serial C-reactive protein-guided computed tomography surveillance and selective omission of defunctioning ileostomy
- What this could lead to
- If successful, this approach could help many rectal cancer patients avoid a temporary ileostomy and its complications after surgery.
- What could go wrong
- This is a small, early-stage study. The surveillance pathway may not catch all leaks, and some patients might still need an ileostomy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Alexandria main university hospital
Alexandria, Please Select, 21111, Egypt
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