RECTAL CANCER PATIENTS
Clinical trials for RECTAL CANCER PATIENTS explained in plain language.
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New pill combo may boost rectal cancer remission before surgery
Disease control Recruiting nowThis study tests whether a newer oral chemotherapy drug (TAS-102) works better than the current standard (capecitabine) when given with radiation before surgery for locally advanced rectal cancer. About 210 adults aged 18-75 with stage II or III rectal cancer will take part. The …
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE3 • Sponsor: Shandong Cancer Hospital and Institute • Aim: Disease control
Last updated May 16, 2026 23:48 UTC
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Robotic surgery showdown: single port vs. multi port for rectal cancer
Disease control Recruiting nowThis study compares two robotic surgery methods for rectal cancer: single-port (one small cut) and multi-port (several cuts). The goal is to see which is safer and leads to fewer complications. About 40 adults with stage I to III rectal cancer will take part. The results will hel…
Matched conditions: RECTAL CANCER PATIENTS
Phase: NA • Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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Real-Time tissue check may spare rectal cancer patients from extensive surgery
Disease control Recruiting nowThis study tests a strategy for people with low rectal cancer who have had radiation therapy. During surgery, a piece of the tumor is removed and immediately checked under a microscope. If the cancer is only in the surface layer, no further surgery is needed. If it is deeper, the…
Matched conditions: RECTAL CANCER PATIENTS
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated May 16, 2026 23:38 UTC
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New combo therapy aims to shrink rectal tumors before surgery
Disease control Recruiting nowThis study tests whether adding an immunotherapy drug (PD-1 inhibitor) to a standard treatment plan (short-course radiation, chemotherapy, and a targeted therapy) can improve outcomes for people with locally advanced rectal cancer. About 104 participants will receive the standard…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated May 16, 2026 23:36 UTC
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New combo therapy aims to shrink rectal tumors before surgery
Disease control Recruiting nowThis study tests whether giving chemotherapy plus the immunotherapy drug tislelizumab before surgery can help shrink tumors in people with locally advanced rectal cancer. About 35 adults with stage T3 or T4 rectal cancer will receive three cycles of the drug combination, then hav…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: The Affiliated Hospital of Qingdao University • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New combo therapy aims to shrink rectal tumors before surgery
Disease control Recruiting nowThis study tests whether a short course of radiation combined with immunotherapy (iparomlimab and tuvonralimab), a targeted drug (regorafenib), and chemotherapy (CAPOX) can shrink advanced rectal cancer before surgery. About 88 adults with a specific type of rectal cancer will be…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Study explores hidden side effects of rectal cancer care in women
Knowledge-focused Recruiting nowThis study aims to understand the sexual and gynecological problems women may face after treatment for rectal cancer. Researchers will ask 15 women who are in remission to fill out questionnaires about their symptoms. The goal is to learn how common these issues are and what fact…
Matched conditions: RECTAL CANCER PATIENTS
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 16, 2026 23:38 UTC
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New trial aims to see if chemoradiation affects cancer cells in the blood
Knowledge-focused Recruiting nowThis study looks at 120 people with stage II or III rectal cancer to see if getting chemotherapy and radiation before surgery changes the number of cancer cells found in the blood, compared to having surgery alone. The goal is to learn more about how these treatments work and hel…
Matched conditions: RECTAL CANCER PATIENTS
Phase: NA • Sponsor: University Hospital Ostrava • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC