New radiation boost strategy aims to spare rectal cancer patients from surgery
NCT ID NCT03051464
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study tests two ways of giving extra radiation after standard chemoradiation to people with early-stage rectal cancer. The goal is to see which method helps more people achieve a complete response, so they can avoid major surgery and keep their rectum. About 131 participants will be randomly assigned to receive either an external beam boost or a brachytherapy boost.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre hospitalier universitaire de Québec
RECRUITINGQuébec, Quebec, G2L2Z3, Canada
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Jewish General Hospital
RECRUITINGMontreal, Quebec, H3T 1E2, Canada
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Le Centre Hospitalier de l'Université de Montreal
RECRUITINGMontreal, Quebec, H2X0A9, Canada
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New drug cocktail aims to shrink rectal tumors and avoid colostomy
- Vaccinia virus targets rectal tumors in new immunotherapy combo
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- New triple therapy aims to wipe out rectal cancer before surgery