New study investigates whether chemoradiation before surgery reduces cancer cells in the blood
NCT ID NCT07194616
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This clinical trial is looking at how chemoradiation given before surgery affects circulating tumor cells (CTCs) in patients with stage II-III rectal cancer. CTCs are cancer cells that travel in the blood and may indicate how likely the cancer is to spread. The study will compare two groups: one that gets chemoradiation followed by surgery, and another that has surgery alone. By tracking CTCs over time, researchers hope to learn more about which treatment approach might be better at controlling the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fluoropyrimidine-based chemotherapy and radiotherapy
What this could lead to
If successful, this study could help doctors understand whether chemoradiation before surgery reduces the spread of cancer cells in the bloodstream, potentially guiding better treatment decisions for rectal cancer.
What could go wrong
This is an early-stage observational trial focused on a biomarker, not a direct treatment outcome. The results may not lead to immediate changes in patient care, and the sample size is relatively small.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RECTAL CANCER PATIENTS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Municipal Hospital Ostrava - Fifejdy
RECRUITINGOstrava, 728 80, Czechia
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Palacky University Olomouc, Faculty of Medicine
RECRUITINGOlomouc, Czechia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
University Hospital Olomouc
RECRUITINGOlomouc, 779 00, Czechia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
University Hospital Ostrava
RECRUITINGOstrava, 70852, Czechia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact