New drug combo could boost rectal cancer remission before surgery

NCT ID NCT06850090

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial compares two different oral chemotherapy drugs given alongside radiation before surgery for locally advanced rectal cancer. The standard drug, capecitabine, is being tested against a newer drug called TAS-102. The goal is to see if TAS-102 leads to more tumors completely disappearing before surgery. About 210 adults aged 18-75 with stage II or III rectal cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shandong Cancer Hospital and Institute

    RECRUITING

    Jinan, Shandong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••