RECTAL CANCER PATIENTS
Clinical trials for RECTAL CANCER PATIENTS explained in plain language.
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New Pre-Surgery combo aims to shrink rectal tumors and save the rectum
Disease control Not yet recruitingThis study tests a new treatment plan for adults with locally advanced rectal cancer that hasn't spread. Participants get a week of radiation, then 8 cycles of three drugs (chemotherapy and immunotherapy) before surgery. The goal is to shrink the tumor enough to cure the cancer o…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: Guangdong Provincial People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Could a diabetes drug boost rectal cancer treatment?
Disease control Not yet recruitingThis study tests whether adding a weight-loss medication (a GLP-1 drug) to standard chemo-radiation before surgery helps rectal cancer patients with a high BMI. About 42 participants will either get the drug plus standard treatment or standard treatment alone. Researchers will me…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: St. James's Hospital, Ireland • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Immunotherapy plus chemo shows promise in rectal cancer trial
Disease control Not yet recruitingThis phase 2 trial tests whether adding an immunotherapy drug (iparomlimab and tuvonralimab) to standard chemoradiotherapy before surgery can improve outcomes for people with locally advanced rectal cancer. About 108 participants will be randomly assigned to receive either the st…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: Zhongnan Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Immunotherapy combo aims to wipe out High-Risk rectal cancer before surgery
Disease control Not yet recruitingThis study is testing whether adding an immunotherapy drug (PD-1 inhibitor) to standard chemoradiation can better shrink or eliminate tumors in people with locally advanced rectal cancer that has a high chance of coming back. About 30 participants will receive the combination tre…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of University of Science and Technology of China • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Which predicts survival better: shrinking the tumor or clearing the lymph nodes?
Knowledge-focused Not yet recruitingThis study looks at 100 adults with advanced rectal cancer who received total neoadjuvant therapy (a combination of chemotherapy and radiation before surgery). Researchers want to see whether the response in the lymph nodes or the primary tumor better predicts how long patients s…
Matched conditions: RECTAL CANCER PATIENTS
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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New study tests if removing rectal tumors through the anus reduces pain and wound issues
Knowledge-focused Not yet recruitingThis study looks at two ways to remove rectal cancer tumors. The newer method removes the tumor through the anus, avoiding extra cuts in the belly. The goal is to see if this leads to fewer wound problems and less pain after surgery. The study will review records from 190 adult p…
Matched conditions: RECTAL CANCER PATIENTS
Sponsor: Istituto Clinico Humanitas • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC