RECTAL CANCER PATIENTS
Clinical trials for RECTAL CANCER PATIENTS explained in plain language.
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Could a citrus supplement boost chemo for rectal cancer?
Disease control Not yet recruitingThis study tests whether adding citrus flavonoid tablets (Aimailang) to standard chemotherapy (mFOLFOX) can shrink tumors more effectively before surgery in people with a specific type of advanced rectal cancer. About 236 participants with high YWHAB protein levels will receive e…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New combo therapy aims to shrink rectal tumors and avoid surgery
Disease control Not yet recruitingThis study tests whether adding an immunotherapy drug (QL1706) to standard chemoradiation can help shrink advanced rectal cancer more effectively. About 108 adults with stage 2 or 3 rectal cancer will be randomly assigned to receive either the standard treatment or the standard t…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: Zhongnan Hospital • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New combo therapy may let rectal cancer patients skip surgery
Disease control Not yet recruitingThis study tests a new approach for adults with locally advanced rectal cancer that hasn't spread. Participants get a short course of radiation followed by a mix of two chemotherapy drugs and an immunotherapy drug. The goal is to shrink the tumor enough so that surgery may not be…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: Guangdong Provincial People's Hospital • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Could a diabetes drug boost rectal cancer treatment?
Disease control Not yet recruitingThis study tests whether adding a GLP-1 weight-loss drug (like semaglutide) to standard chemo-radiation before surgery helps rectal cancer patients with a high BMI. Researchers will measure weight loss, tumor response, and survival in 42 participants. The goal is to see if the dr…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: St. James's Hospital, Ireland • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New combo therapy aims to wipe out high-risk rectal cancer before surgery
Disease control Not yet recruitingThis study tests whether combining chemotherapy, radiation, and an immunotherapy drug can completely eliminate tumors in people with locally advanced rectal cancer that has a high chance of coming back. About 30 participants will receive this treatment before any surgery. The mai…
Matched conditions: RECTAL CANCER PATIENTS
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of University of Science and Technology of China • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New rectal cancer surgery method may cut recovery time
Knowledge-focused Not yet recruitingThis study looks at two ways to remove rectal cancer using minimally invasive surgery. One method removes the tumor through the anus, avoiding extra cuts in the belly. The other uses a small belly cut. Researchers want to see if the newer method leads to fewer wound problems and …
Matched conditions: RECTAL CANCER PATIENTS
Sponsor: Istituto Clinico Humanitas • Aim: Knowledge-focused
Last updated May 17, 2026 03:17 UTC
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Which predicts survival better: lymph nodes or tumor shrinkage?
Knowledge-focused Not yet recruitingThis study looks at 100 adults with advanced rectal cancer who received total neoadjuvant therapy (a combination of chemotherapy and radiation before surgery). Researchers want to see whether the status of lymph nodes after treatment or the shrinkage of the main tumor better pred…
Matched conditions: RECTAL CANCER PATIENTS
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated May 17, 2026 03:08 UTC