Can a common drug reverse Poison-Induced delirium? new study says yes

NCT ID NCT07545382

Completed Symptom relief Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether rivastigmine can safely reverse delirium caused by poisoning from certain drugs like clozapine or tricyclic antidepressants. 100 patients at a poison center received rivastigmine, and doctors measured their consciousness and agitation levels. The goal was to see if the drug could help patients wake up and become calm and alert.

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Conditions

The condition(s) this trial relates to.

acute tricyclic antidepressant poisoning drug psychosis drug-induced mental disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTICHOLINERGIC DELIRIUM ANTIPSYCHOTIC TOXICITY CLOZAPINE POISONING CNS DEPRESSION HYPOACTIVE DELIRIUM PROCYCLIDINE INDUCED DELIRIUM TRICYCLIC ANTIDEPRESSANT POISONING

Contacts and locations

Locations

Poison Control Center (PCC), Alexandria University Main Hospital

Alexandria, 21131, Egypt

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