Can slower dialysis fluid flow still clean blood effectively?

NCT ID NCT07360769

Completed Knowledge-focused Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether using a lower dialysate flow rate (300 ml/min instead of the usual 500 ml/min) affects how well dialysis cleans the blood, how quickly patients recover after treatment, and their overall quality of life. Eighty adults with end-stage kidney disease on maintenance hemodialysis took part. Each patient had one week of standard flow and one week of low flow to compare results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lower dialysate flow rate (300 ml/min)
What this could lead to: If successful, this could show that using less dialysate fluid is safe and effective, potentially reducing costs and environmental waste in dialysis.
What could go wrong: This is a small, completed study with only 80 participants, so results may not apply to all kidney patients. Lower flow might reduce dialysis adequacy for some individuals.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

END STAGE KIDNEY DISEASE (ESRD)

Contacts and locations

Locations

Faculty of Medicine Alexandria University

Alexandria, Egypt

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