Ozone and PRP combo shows promise for jaw pain relief
NCT ID NCT07452289
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a procedure called arthrocentesis (joint washing) using ozonated water, with or without a platelet-rich plasma (PRP) injection, for people with a displaced jaw disc. The goal was to see if adding PRP improves mouth opening, reduces pain, and lowers inflammation. Twenty patients who had not responded to other treatments took part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ozonated water and platelet-rich plasma (PRP) injection
- What this could lead to
- If this works, it could offer a more effective treatment for TMJ pain and limited mouth opening, improving quality of life.
- What could go wrong
- This is a very small, early-stage trial with only 20 participants, so results may not apply to everyone. The treatment is not a cure and only aims to ease symptoms.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt
Alexandria, Azarita, 00203, Egypt
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