POST OPERATIVE PAIN

This study looked at two different ways to numb the belly area to reduce pain after laparoscopic hernia repair. 90 adults received either a modified thoracoabdominal nerve block (M-TAPA) or a standard transversus abdominis plane (TAP) block. The goal was to see which method bette…

This study tested whether a non-opioid pain medicine called suzetrigine can control pain after outpatient facial plastic surgery and reduce the need for opioid pills. 100 adults took part. Researchers measured how many opioid pills were used and how much pain people felt. The goa…

This study tested three different pain-relief methods in 102 adults having lung surgery through a single small cut. The goal was to see which method keeps patients comfortable the longest after surgery. Researchers measured how soon patients needed extra pain medicine and how str…

This study tested a new medicine called MR-107A-02 to see if it can safely relieve pain after bunionectomy (foot surgery). About 410 adults took part. The goal was to measure how well the drug reduces pain and whether it can cut down the need for stronger opioid painkillers.

This study looked at how well three different oral painkillers reduce pain after root canal treatment. One hundred adults with tooth pain took part. Researchers measured their pain levels using a simple 0-to-10 scale to see which medication worked best.

This study compared two pain relief methods for people having their bladder removed (radical cystectomy). Twenty adults received either a thoracic epidural or an ultrasound-guided nerve block. Researchers measured how long pain relief lasted, pain scores, and the amount of extra …

This study tested two different nerve blocks to manage pain after midshaft clavicle (collarbone) surgery in 50 adults. One block targets the shoulder area, the other the chest wall. Researchers measured how long pain relief lasted and whether one method caused less diaphragm weak…

This study looked at whether giving ketamine during surgery and methadone after surgery can prevent a condition called opioid-induced hyperalgesia, where painkillers actually make you more sensitive to pain. 113 adults having open colorectal surgery took part. The goal was to see…

This study tested whether adding magnesium to a standard numbing medicine (bupivacaine) improves pain control after total knee replacement. 94 adults having knee surgery received either the combination or bupivacaine alone in a nerve block. The goal was to see if the magnesium mi…

This study tested whether a single injection of F14 (a long-acting pain reliever) given during knee replacement surgery can reduce pain and the need for opioid painkillers afterward. 151 adults aged 45 to 80 who had a knee replaced took part. The goal was to see if F14 plus stand…

This study tested an experimental pain medication called MR-107A-02 in 579 adults who had hernia surgery. The goal was to see if it reduces pain better than a placebo or an existing painkiller. Participants rated their pain on a 0-10 scale, and researchers also tracked how much e…

This study tested two pain-relief methods after breast removal surgery: a nerve block (erector spinae plane block) versus numbing medicine injected into the wound. 37 adults participated. The main goal was to see how much morphine patients needed in the first day after surgery. R…

This study looked at whether the 4-7-8 breathing technique (a slow, patterned breathing exercise) can help reduce pain, nausea, and vomiting in people who just had weight-loss surgery. Sixty adults were split into two groups: one practiced the breathing technique hourly for 24 ho…

This study tested two different ultrasound-guided nerve blocks to see which one provides better pain relief after inguinal hernia repair. 43 men undergoing hernia surgery received one of the two blocks. The goal was to find the most effective way to reduce post-operative pain.

This study compared two types of nerve blocks (erector spinae plane block and serratus anterior plane block) for pain relief after breast reduction surgery. Eighty women received one of the two blocks before surgery, and researchers measured their pain scores and how much opioid …

This study tested whether adding dexmedetomidine to a standard numbing medicine (bupivacaine) in nerve blocks could provide better pain relief after heart surgery. Sixty adults having open-heart surgery through a chest incision received the nerve block. The main goal was to see h…

This study tested a new approach for knee replacement surgery in 70 people with severe knee arthritis. The idea was to add a nerve-freezing procedure during the operation to see if it reduces pain and improves knee function afterward. The goal is to help people recover better and…

This study looked at 168 adults with a silent tooth infection (asymptomatic apical periodontitis) to see if different root canal shaping tools affect pain after the procedure. Participants were split into groups using different combinations of files, including the Wave One Gold. …

This study tested whether multi-port epidural catheters work better than single-port ones for pain relief after chest or upper belly surgery. 240 adults took part. The main goal was to see if multi-port catheters reduce the need for extra pain medicine or catheter replacement.

This study looked at whether a quadratus lumborum (QL) nerve block can lower pain and the need for opioid painkillers after robotic surgery for pelvic organ prolapse. 70 women were randomly assigned to receive either standard enhanced recovery care or a QL block. The main goal wa…

This study looked at whether adding the steroid dexamethasone to a standard nerve block (adductor canal block) can provide longer pain relief after total knee replacement surgery. 66 adults scheduled for knee replacement received the nerve block with or without dexamethasone. The…

This study looked at whether using a sonic device to clean the tooth during a root canal can lower pain afterward. Fifty-eight adults needing root canal treatment were randomly assigned to get either the sonic cleaning or the standard syringe method. Their pain was measured befor…

This study tested two types of cold therapy (cryotherapy) to reduce pain and inflammation after root canal treatment in 30 adults with infected lower premolars. One group used an ice pack on the cheek for 30 minutes, another had a cold saline rinse inside the tooth, and a control…

This study looked at 63 adults who had heart surgery through a small chest cut. It compared two ways to manage pain after surgery: freezing the nerves (cryoanalgesia) and a nerve block (BRILMA). The goal was to see which method provides better pain relief and reduces long-term ne…

This study tested whether adding dexamethasone or magnesium sulfate to a standard numbing medicine (bupivacaine) in a nerve block could provide longer pain relief after total hip replacement. 66 adults having hip surgery received one of the two combinations. Researchers measured …

This study tested whether a numbing medicine injected near the chest wall could reduce the need for strong painkillers after heart surgery. 340 adults having open-heart surgery through a breastbone incision took part. Half received the nerve block with a local anesthetic, and the…

This study looked at whether using sonic devices (EDDY or EndoActivator) with or without a laser during root canal treatment could lower pain after the procedure. Eighty adults with infected single-root teeth were randomly assigned to one of four cleaning methods. Patients report…

This study tested two methods of giving a nerve block to control pain after lumbar spinal fusion surgery. 52 adults having elective surgery received either an ultrasound-guided or a surgeon-placed block using a mix of numbing medicine and a drug that prolongs pain relief. The goa…

This study tested three different nerve blocks to see which one works best for pain after shoulder surgery. Forty adults having shoulder surgery received one of the blocks, and their pain was measured using a simple 0-to-100 scale. The goal was to find a block that controls pain …

This study looked at 60 adults having partial hip replacement to compare two spinal anesthesia methods: hypobaric (lighter) and hyperbaric (heavier). The goal was to see which one keeps blood pressure more stable and reduces pain after surgery. Researchers measured pain using a 0…

This study looked at three ways to manage pain during and after hip surgery in people over 60. One group got a single spinal injection, another got a continuous spinal injection through a tiny tube, and the third got general anesthesia. The goal was to see which method worked bes…

This study looked at whether a genetic test can help doctors choose safer and more effective pain medicines for women after gynecologic surgery. About 112 women participated, and half had their painkiller choice guided by the test while the other half received standard care. The …