New painkiller injection could ease recovery after hernia repair

NCT ID NCT05813847

Completed Symptom relief Sponsor: Cali Pharmaceuticals LLC Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new local anesthetic called CPL-01 to control pain after open inguinal hernia repair. 518 adults received either CPL-01, a placebo, or an active control injection right after surgery. Researchers measured pain levels during activity over time to see if CPL-01 provides better relief than standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CPL-01 (a local anesthetic injection)
What this could lead to: If it works, this could provide a new way to manage pain after hernia surgery, potentially reducing the need for opioids.
What could go wrong: This is a completed Phase 3 trial, but results are not yet public. The treatment may not prove better than existing options, and any new drug carries risks of side effects like allergic reactions or injection-site issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hernia, Inguinal Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HERNIA, INGUINAL POST-OPERATIVE PAIN

Contacts and locations

Locations

Todd Bertoch

Salt Lake City, Utah, 84101, United States

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