New painkiller injection could ease recovery after hernia repair

NCT ID NCT05813847

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new local anesthetic called CPL-01 to control pain after open inguinal hernia repair. 518 adults received either CPL-01, a placebo, or an active control injection right after surgery. Researchers measured pain levels during activity over time to see if CPL-01 provides better relief than standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CPL-01 (a local anesthetic injection)

What this could lead to

If it works, this could provide a new way to manage pain after hernia surgery, potentially reducing the need for opioids.

What could go wrong

This is a completed Phase 3 trial, but results are not yet public. The treatment may not prove better than existing options, and any new drug carries risks of side effects like allergic reactions or injection-site issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hernia, Inguinal Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Todd Bertoch

    Salt Lake City, Utah, 84101, United States