Knee replacement patients may need less morphine with gabapentin

NCT ID NCT01307202

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether giving multiple doses of gabapentin before and after total knee replacement surgery can reduce the amount of morphine needed for pain. 101 adults having elective knee replacement took part. The goal was to see if gabapentin could lower pain and morphine-related side effects like nausea and dizziness.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hamilton Health Sciences

    Hamilton, Ontario, L8N 3Z5, Canada