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New drug aims to ease Post-Surgery pain without opioids

NCT ID NCT06215859

Completed Symptom relief Sponsor: Viatris Specialty LLC Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new drug called MR-107A-02 for treating acute pain after hernia repair surgery. About 579 adults took part, comparing the drug to a placebo and to tramadol, a standard painkiller. The goal was to see if MR-107A-02 reduces pain intensity and the need for extra opioid rescue medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
MR-107A-02 (a pain-relief drug)
What this could lead to
If it works, this could offer a new option for managing pain after hernia surgery, possibly reducing the need for opioid rescue medication.
What could go wrong
This is a completed Phase 3 trial, but results are not yet published. The drug may not prove more effective than existing treatments like tramadol, and all pain drugs carry side effects such as nausea or dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acute Pain Pain Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PAIN PAIN POST-OPERATIVE PAIN

Contacts and locations

Locations

  • Investigator site 201

    Salt Lake City, Utah, 84107, United States

  • Investigator site 202

    Anaheim, California, 92801, United States

  • Investigator site 203

    San Antonio, Texas, 78240, United States

  • Investigator site 204

    Houston, Texas, 77008, United States

  • Investigator site 205

    Wichita, Kansas, 67214, United States

  • Investigator site 206

    Tampa, Florida, 33613, United States

  • Investigator site 207

    Atlanta, Georgia, 30331, United States

  • Investigator site 208

    Riverside, California, 92501, United States

  • Investigator site 210

    Sheffield, Alabama, 35660, United States

  • Investigator site 211

    Miami, Florida, 33014, United States

  • Investigator site 212

    Bellaire, Texas, 77401, United States

  • Investigator site 213

    Phoenix, Arizona, 85053, United States

  • Investigator site 214

    San Antonio, Texas, 78258, United States

  • Investigator site 215

    Carrollton, Texas, 75006, United States

  • Investigator site 216

    McAllen, Texas, 78501, United States

  • Investigator site 219

    San Antonio, Texas, 78229, United States

  • Investigator site 222

    Bakersfield, California, 93301, United States

  • Investigator site 224

    Eau Claire, Wisconsin, 54701, United States

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