New shot could cut opioid use after bunion surgery
NCT ID NCT05831449
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested an experimental long-acting local anesthetic called CPL-01 in 616 people having bunion surgery. The goal was to see if it reduces pain and the need for opioid painkillers after the operation compared to a standard anesthetic or a placebo. Participants received the injection during surgery and were monitored for pain levels and any rescue medication use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CPL-01 (long-acting ropivacaine local anesthetic injection)
What this could lead to
If it works, CPL-01 could provide longer-lasting pain relief after foot surgery and reduce the need for opioid painkillers.
What could go wrong
This is a completed Phase 3 trial, but results are not yet published. The drug may not prove significantly better than existing anesthetics or placebo, and individual responses to pain medication vary.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POST OPERATIVE PAIN are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Todd Bertoch
Salt Lake City, Utah, 84101, United States