POST OPERATIVE PAIN
Clinical trials for POST OPERATIVE PAIN explained in plain language.
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Nerve block may ease pain after thyroid surgery
Symptom relief OngoingThis study looks at whether a numbing injection in the neck (called a cervical block) plus local anesthetic can lower pain, nausea, and the need for strong painkillers after thyroid surgery. About 74 adults having their thyroid removed will be randomly assigned to get either the …
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Freezing nerves before knee replacement may cut opioid use
Symptom relief OngoingThis study tests a treatment called cryoneurolysis, which uses cold to temporarily freeze nerves around the knee before replacement surgery. The goal is to see if it reduces pain and the need for strong painkillers (opioids) after surgery. About 100 adults scheduled for knee repl…
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: Esbjerg Hospital - University Hospital of Southern Denmark • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Which pain block works best for hip surgery? new study aims to find out
Symptom relief OngoingThis study compares two types of nerve blocks (SFIB and PENG) to see which provides better pain relief after hip replacement surgery. Sixty adults undergoing hip surgery will receive one of the two blocks. The main goal is to measure how much morphine they need in the first 24 ho…
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: Balikesir University • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Which root canal filling hurts less? new study aims to find out
Symptom relief OngoingThis study looks at two different medicines placed inside a tooth during root canal treatment to see which one causes less pain and helps the infection heal better. Eighty adults with infected front teeth will receive one of the two medicines and report their pain levels over a w…
Matched conditions: POST OPERATIVE PAIN
Phase: NA • Sponsor: Ege University • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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New combo drug approach aims to cut opioid use after joint surgery
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether taking two pain medicines (tramadol and oxycodone) together works better than taking oxycodone alone after knee or hip replacement surgery. The goal is to see if the combination reduces the total amount of opioids needed and lowers side effects. About …
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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Pain relief study for opioid users pulled before it started
Symptom relief TerminatedThis study aimed to see if a tiny dose of buprenorphine/naloxone could help manage pain after surgery in people who already take strong painkillers. It planned to compare pain scores, opioid use, and hospital stay length between the micro-dose group and standard care. However, th…
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 08, 2026 12:04 UTC
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Nose job pain relief showdown: which drug works longer?
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether adding dexamethasone or dexmedetomidine to a standard numbing medicine (bupivacaine) can provide longer pain relief after rhinoplasty (nose job). About 90 adults undergoing nose surgery will receive one of these combinations as a nerve block. The main goa…
Matched conditions: POST OPERATIVE PAIN
Phase: PHASE1 • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 08, 2026 12:03 UTC
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New study seeks to ease pain after mastectomy
Knowledge-focused OngoingThis study observes 800 women undergoing mastectomy to see if a PECS nerve block with liposomal bupivacaine improves pain control and quality of recovery 72 hours after surgery. Some women receive the block, others do not. The goal is to understand which approach leads to better …
Matched conditions: POST OPERATIVE PAIN
Sponsor: Endeavor Health • Aim: Knowledge-focused
Last updated May 17, 2026 00:47 UTC