Neck block may cut thyroid surgery pain and opioid use

NCT ID NCT05805423

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a nerve block (bilateral superficial cervical plexus block) plus local anesthetic can reduce pain, nausea, and opioid use after thyroid surgery. 74 adults having a partial or total thyroid removal are randomly assigned to receive either the nerve block or a placebo injection, both with local wound infiltration. The goal is to see if the block improves recovery and quality of life in the first days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If it works, this could offer a simple way to reduce pain and nausea after thyroid surgery, possibly lowering the need for opioids.
What could go wrong
This is a small, early-stage trial (74 people) testing a common procedure, so results may not be dramatic or widely applicable. The nerve block itself carries small risks like bruising or temporary nerve irritation.

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Conditions

The condition(s) this trial relates to.

opioid abuse Pain, Postoperative Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UC Davis Medical Center

    Sacramento, California, 95817, United States

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