FATIGUE

This study looked at whether giving liver transplant patients simple exercise guides (a brochure or a video) helps them become more active, feel less tired, and reduce the burden on their caregivers. Over 100 adults who had a liver transplant were split into three groups: one got…

This study looked at whether a structured physical activity program, along with health education materials, could help prevent colon cancer from returning in people who had surgery and chemotherapy for high-risk stage II or stage III colon cancer. A total of 889 participants were…

This study tested whether starting a personalized exercise program before breast cancer surgery helps women recover better. Thirty female patients followed the program for 12 months. Researchers measured shoulder movement, pain, arm function, fatigue, and quality of life to see i…

This study tested three types of cognitive behavioral therapy (relaxation, activity planning, and changing thoughts) delivered by video call to help with fatigue in people with multiple sclerosis. 21 adults with MS and chronic fatigue took part. The goal was to see if the therapy…

This study looked at whether a gentle exercise program called Gyrokinesis can help reduce fatigue in children and teens who were treated for a brain tumor. 80 participants who had finished active treatment at least a year earlier took part. The study measured fatigue levels and w…

This study tested whether a non-invasive device that stimulates a nerve in the ear (transcutaneous vagus nerve stimulation) can help young athletes recover more quickly after exercise. Forty healthy amateur football players aged 18-25 participated. The researchers measured breath…

This study tested whether certain health and wellness products can help reduce fatigue in adults. 750 participants took either the product or a placebo, and researchers tracked changes in tiredness, thinking ability, and sleep quality over time. The goal was to see if these produ…

This study looked at whether kinesiological taping (a special tape placed on the skin) or foot massage can help women who had a C-section feel less pain, fatigue, and mood changes. 97 new mothers were split into three groups: one got taping, one got foot massage, and one got stan…

This study tested whether visiting a virtual museum using VR glasses during chemotherapy can reduce pain, fatigue, and anxiety. 64 patients receiving chemotherapy were split into two groups: one group wore VR glasses to tour a virtual museum for about 20 minutes per session over …

This study tested different doses of light therapy to see which works best for improving sleep in people with Parkinson's disease. 203 participants received either bright-white or dim-red light at different times of day. The goal was to find a safe, effective way to ease sleep tr…

This study looked at whether nursing care based on the Levine Conservation Model could reduce fatigue, nerve pain, and anxiety in people with colorectal cancer getting chemotherapy. Sixty-eight patients took part. The approach focused on helping patients conserve energy and cope …

This early-phase study tested whether a supplement made from muscadine grapes could reduce fatigue in people aged 70 and older who had been treated for cancer. Sixty-four participants took either the grape extract or a placebo for 12 weeks. The main goal was to see if fatigue sco…

This study tested whether laughter yoga can reduce fatigue, improve sleep quality, and boost psychological well-being in people with multiple sclerosis (MS). Forty adults with MS took part, and their symptoms were measured before and after six weeks of laughter yoga sessions. The…

This study tested whether filtering certain substances out of the blood (a process called apheresis) can help relieve severe fatigue in people with Long COVID. 63 adults with chronic fatigue syndrome after a COVID-19 infection took part. Half received the real treatment, half a s…

This study tested a health and wellness product called Radicle Energy to see if it could help reduce fatigue and improve thinking. About 500 adults took either the product or a placebo (fake product) without knowing which they got. The goal was to measure changes in tiredness and…

This study tested whether smelling geranium essential oil can help reduce fatigue and improve sleep in people undergoing hemodialysis for kidney failure. 90 adults on dialysis took part in a crossover trial where they received both the aromatherapy and a placebo at different time…

This study tested if hand reflexology massage can help reduce fatigue and anxiety in adults receiving maintenance hemodialysis for end-stage kidney disease. 70 participants were randomly assigned to either receive eight 21-minute hand reflexology sessions during their regular dia…

This study tested an 8-week exercise program done at home via video calls to see if it could reduce fatigue and improve quality of life in nurses with long COVID. 68 nurses who had long COVID symptoms like tiredness and breathing trouble took part. The program aimed to boost hear…

This study looked at whether acupressure, a technique where you apply gentle pressure to specific spots on the body, can help reduce severe tiredness in women who have had ovarian cancer. 171 survivors took part, and researchers measured their fatigue and quality of life over 24 …

This study tested a stepped-care program delivered by phone to help cancer survivors living in rural areas manage emotional distress like anxiety and depression. 68 adults who had finished cancer treatment for breast, colorectal, prostate, gynecologic cancers, or non-Hodgkin's ly…

This study looked at whether progressive relaxation exercises can help people with type 2 diabetes who have nerve pain, fatigue, and poor sleep. 88 adults took part, and researchers measured changes in pain, tiredness, and sleep quality. The goal was to see if a simple, non-drug …

This study looked at whether foot reflexology massage could help people with epilepsy. Researchers measured changes in seizure frequency, fatigue, stress, and sleep quality. 70 adults with epilepsy took part, and the goal was to see if this gentle foot therapy could improve their…

This study tested whether foot reflexology—a type of focused foot massage—could help people with migraines feel less pain and fatigue and improve their daily life. 78 adults with migraines took part; half received 10 reflexology sessions over 5 weeks, while the other half continu…

This study tested a health and wellness product to see if it helps reduce fatigue. Over 500 adults in the U.S. took either the product or a placebo, and researchers measured changes in tiredness, thinking, and sleep. The goal was to find out if the product works better than a dum…

This study tested a program to help young adult cancer survivors (ages 18-39) with obesity lose weight and manage symptoms like pain, fatigue, and distress. The goal was to reduce their risk of heart disease. 38 survivors took part in a pilot trial to see if the program was feasi…

This study tested a health and wellness product in 500 perimenopausal women aged 40 and older to see if it could improve stress, sleep, and menopause-related issues. Participants took either the product or a placebo, and researchers measured changes in perceived stress and other …

This study looked at whether a 12-week treadmill walking program could boost physical fitness, reduce fatigue, and improve mood in people with traumatic brain injury (TBI). Thirteen adults with TBI who were not physically active took part. They exercised three times a week, and r…

This study looked at whether a home-based exercise program can help people with non-small cell lung cancer manage severe tiredness after surgery. 235 adults took part. The program was designed to be simple, safe, and low-cost. The goal was to reduce fatigue and improve quality of…

This study looked at whether two non-drug methods—therapeutic touch (balancing energy) and emotional freedom technique (tapping on acupoints)—can help new mothers feel less tired and improve their mood after childbirth. Sixty women who had a vaginal birth were split into three gr…

This study tested whether listening to live music, a special flute sound, or interacting with a robotic parrot could help people on dialysis feel less anxious and less tired. 64 adults receiving regular dialysis took part. Researchers measured their anxiety and fatigue levels bef…

This study tested whether a supervised exercise program can reduce fatigue and improve quality of life in people with unstable shoulder. 108 adults who had at least one shoulder dislocation in the past year took part. Participants either did a special exercise program guided by a…

This study looked at whether MitoQ, a dietary supplement, can help reduce fatigue in people with multiple sclerosis (MS). 45 participants with MS and significant fatigue took either MitoQ or a placebo daily for 12 weeks. The main goal was to see if MitoQ improved fatigue scores c…

This study looked at whether music therapy can ease fatigue and improve certain blood test results in people with acute myeloid leukemia who are receiving chemotherapy for the first time. Sixty adults took part, and researchers measured their fatigue levels and lab values like wh…

This study looked at whether watching exercise videos before doing the exercises helps older adults think better, keep their balance, feel less tired, and move more easily. 162 people aged 65 and older took part. Some did regular exercise, some watched exercise videos then exerci…

This study tested whether a 20-minute virtual reality session could help patients feel less pain and fatigue after a liver transplant. 84 patients were split into two groups: one tried virtual reality, the other got standard care. Researchers measured pain, fatigue, and vital sig…

This pilot study tested whether vagal nerve stimulation could reduce fatigue and headaches in people with Post-COVID syndrome. 18 participants used the device and reported changes in their symptoms. The goal was to see if this approach is worth studying further.

This small pilot study tested a cognitive behavioral program to help reduce fatigue in people with chronic kidney disease (CKD). Five adults with moderate-to-severe CKD joined remote sessions to learn strategies for managing tiredness. The main goal was to see if the program was …

This study tested whether a health and wellness product can reduce fatigue in adults. About 1,000 people took either the product or a placebo, and researchers tracked changes in tiredness, sleep quality, and mental focus over time. The goal was to see if the product offers real b…

This study looked at whether taking a daily probiotic mix for three months could help professional dancers feel less tired and stressed. Researchers measured changes in gut bacteria, immune markers, and stress-related substances in the blood. The goal was to see if probiotics cou…

This study tested a non-invasive device that stimulates the vagus nerve (a major nerve in the neck) to see if it can reduce fatigue in people with lupus. 75 adults with lupus and fatigue took part. Half received active stimulation, half received a sham (inactive) device. The goal…

This study tested a new way to measure physical fatigue during everyday tasks like walking and lifting, going beyond just walking tests. Researchers worked with 40 people—stroke survivors and older adults with sarcopenia—to see how their bodies and minds responded to fatigue. The…

This study looked at how cardiac arrest affects thinking, memory, emotions, fatigue, and sleep. About 200 survivors were compared to heart attack patients who did not have a cardiac arrest. Researchers used tests and questionnaires at 7 and 24 months after the event to understand…

This study looked at how apathy (lack of interest or motivation) influences different types of fatigue in older adults with mild neurocognitive disorders. Researchers compared 30 apathetic and 30 non-apathetic participants aged 65-85. Participants wore activity trackers for a wee…

This study looked at whether chemicals in saliva can show if a driver is dangerously sleepy. Over 500 drivers in Belgium gave spit samples during police stops. Researchers compared the samples with how sleepy the drivers felt and looked. The goal is to find a simple test that cou…

This study looked at how prediabetes and type 2 diabetes impact memory, physical abilities, and tiredness in people aged 60 and older. Researchers compared 94 older adults with normal blood sugar, prediabetes, or diabetes using tests for thinking, balance, and fatigue. The goal w…

This study looked at whether listening to self-selected music during warm-up can improve short, intense exercise performance in highly trained futsal players who are fasting for Ramadan. Ten male players did sprint tests with and without music, both during Ramadan and two weeks a…

This study looked at why people with Parkinson's disease often feel very tired. Researchers measured fatigue, mood, sleep, and physical function in 129 adults with Parkinson's. The goal was to find out which factors are most linked to fatigue, helping doctors better understand an…

This study looked at whether a personalized meal plan with more omega-3 fatty acids (found in fish) could help breast cancer survivors manage symptoms like fatigue, pain, depression, and sleep problems. Researchers worked with 98 women who had finished treatment for early-stage b…

This study looked at how doing a mental task at the same time as a physical exercise affects tiredness in healthy adults aged 18-35 and 65-90. Researchers measured changes in arm strength, anxiety, blood pressure, and fatigue using questionnaires and a special device. The goal wa…

This study looked at how a dose of caffeine (6mg per kg of body weight) affects the way healthy adults perform exercises like running, squatting, and jumping. Researchers measured things like knee angles and step rates both when participants were fresh and when they were tired. T…

This study looked at 42 adults with fibromyalgia to find out what factors most affect their ability to function day-to-day. Researchers measured pain, fatigue, muscle strength, balance, sleep, mood, and physical activity using simple tests and questionnaires. The goal was to bett…

This study looked at 134 adults with chronic sinusitis to see if sleep problems and daytime tiredness predict worse thinking skills and quality of life. Participants filled out questionnaires about their symptoms and daily functioning. The goal was to better understand how sinusi…

This study looked at whether a short daytime nap (25 or 45 minutes) helps teenage soccer players run faster and feel less tired. Sixteen male players from a Turkish club tried both nap lengths and a no-nap day. Results showed that napping improved their agility and made them feel…