Walking it off: treadmill training may boost fitness and mood in brain injury survivors
NCT ID NCT01294332
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a 12-week treadmill exercise program can improve cardiorespiratory fitness, reduce fatigue, and boost mood in people with traumatic brain injury (TBI). Thirteen physically inactive adults with TBI walked on a treadmill three times a week for 30 minutes at a target heart rate. Researchers measured changes in peak oxygen consumption, fatigue, and mood before and after the program.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
supervised treadmill aerobic exercise
What this could lead to
If it works, this could show that structured exercise helps improve physical fitness and reduce fatigue and mood problems after traumatic brain injury.
What could go wrong
This is a very small early-phase study with only 13 participants, so results may not apply to everyone. It also requires participants to be able to walk on a treadmill safely, which limits who can take part.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States