Walking it off: treadmill training may boost fitness and mood in brain injury survivors
NCT ID NCT01294332
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study looked at whether a 12-week treadmill exercise program can improve cardiorespiratory fitness, reduce fatigue, and boost mood in people with traumatic brain injury (TBI). Thirteen physically inactive adults with TBI walked on a treadmill three times a week for 30 minutes at a target heart rate. Researchers measured changes in peak oxygen consumption, fatigue, and mood before and after the program.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- supervised treadmill aerobic exercise
- What this could lead to
- If it works, this could show that structured exercise helps improve physical fitness and reduce fatigue and mood problems after traumatic brain injury.
- What could go wrong
- This is a very small early-phase study with only 13 participants, so results may not apply to everyone. It also requires participants to be able to walk on a treadmill safely, which limits who can take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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