Grape extract shows promise for fatigue in older cancer survivors

NCT ID NCT04495751

Completed Symptom relief Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether muscadine grape extract can improve fatigue in people aged 70 and older who have had cancer. 64 participants took either the grape extract or a placebo for 12 weeks. The study measured changes in fatigue and physical function using questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: muscadine grape extract
What this could lead to: If it works, this could point toward a natural supplement to help reduce fatigue in older cancer survivors.
What could go wrong: This is a very early, small pilot study (64 people) with no definitive results yet. The supplement may not work better than a placebo, and individual results may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for FATIGUE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Fatigue neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FATIGUE

Contacts and locations

Locations

Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, 27157, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.