Can blood filtering beat long COVID fatigue?
NCT ID NCT05954325
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tested a blood filtering procedure called immunoadsorption to see if it reduces fatigue in people with post-COVID syndrome. 63 patients received either the real procedure or a sham version over 14 days. The goal was to measure changes in fatigue and other symptoms like brain fog and post-exertional malaise.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Immunoadsorption (blood filtering procedure)
What this could lead to
If it works, this could point toward a treatment for chronic fatigue in post-COVID syndrome.
What could go wrong
This is a small, early-stage study with no phase. The sham control means the real effect may be small or absent. Risks include discomfort or complications from the procedure.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hannover Medical School
Hanover, Lower Saxony, 30625, Germany