FATIGUE

This study tests different programs to help people at high risk for cancer eat healthier and exercise more. The goal is to see which approach works best to increase physical activity and improve diet. About 337 people with a high BMI, low activity, or poor diet are taking part. T…

This study tests whether personalized coaching on physical activity and nutrition can reduce fatigue in people with lupus. 200 participants are split into two groups: one gets coaching on exercise and diet, the other gets standard lupus self-management education. The main goal is…

This study tests a program called RESET, led by community health workers, to help older adults in Detroit improve their physical and mental well-being. About 456 African American adults aged 50 and older with symptoms like depression, anxiety, chronic pain, or loneliness will tak…

This study tests whether adding a short course of the steroid dexamethasone to a physical activity program can reduce severe fatigue in people with advanced cancer. About 90 participants will be randomly assigned to receive either a high or low dose of dexamethasone along with ex…

This study is testing a mobile app called RN-SLEEP to help nurses who work night shifts sleep better and feel less tired. The app teaches simple skills like relaxation and goal-setting to overcome sleep problems caused by work and home stress. About 76 nurses will try the app or …

This study looks at whether giving blood transfusions to patients who are anemic after leaving the intensive care unit (ICU) can help them feel less tired and recover better. About 346 adults will be randomly assigned to either the usual care (transfusions only if very needed) or…

This study tests a wearable leg support device (Exoband) to see if it reduces tiredness in healthy adults over 65 during everyday tasks like walking, climbing stairs, and avoiding obstacles. Each person tries the tasks with and without the device to compare effort and fatigue. Th…

This study tests whether using mild electrical pulses on the leg muscles can improve confidence in exercise, reduce shortness of breath during activity, and lessen fatigue in people with chronic lung disease (COPD). About 40 adults with mild to severe COPD will receive the stimul…

This small pilot study tests whether a noninvasive brain stimulation technique called rTMS can safely reduce fatigue, brain fog, and other neuropsychiatric symptoms in people with Long-COVID. Ten participants will receive either real or sham rTMS for 15 sessions, followed by 15 o…

This study looks at whether acupressure and back massage can help women who had a C-section feel less pain, less tired, and sleep better. About 111 new mothers will receive these gentle treatments after surgery. The goal is to find safe, drug-free ways to improve recovery without…

This pilot study explores whether chiropractic care can reduce chronic fatigue in adults who have finished cancer treatment and are now cancer-free. About 40 participants will be randomly assigned to receive chiropractic adjustments or continue usual care. The main goal is to see…

This study tested if leg exercises during dialysis or using a breathing device (incentive spirometer) can reduce fatigue and improve sleep quality. 102 adults on hemodialysis were split into three groups: leg exercise, breathing exercise, or usual care. After one month, researche…

This study aimed to see if holistic pastoral counseling could help people manage stress at work and in daily life. It was designed for unmarried Alaska Medicaid recipients aged 22 and older who had internet access and a Bible. However, the study was withdrawn before any participa…

This study looks at how exercise changes the gut microbiome in breast cancer survivors and whether those changes help reduce fatigue and other symptoms. About 126 women who have finished primary cancer treatment will take part. Researchers will measure gut bacteria from stool sam…

This study tests a simple idea: giving doctors a short summary of each patient's work-related challenges before their appointment. The goal is to help people with muscle pain, anxiety, depression, or stress return to work faster. About 1180 adults in Norway will take part, and re…

This study looks at how sleep problems like apnea, insomnia, and poor sleep quality are linked to heart disease and diabetes in rural areas of the southern U.S. About 3,680 adults already part of a larger health study will wear sleep trackers and answer questionnaires. The goal i…

This study looks at how joint flexibility, balance, and tiredness affect climbing performance in both elite and amateur climbers. Researchers will test 60 healthy climbers to see if flexible joints help or hurt, and how fatigue impacts reaction time and safety. The goal is to und…

This study looks at whether the Norwegian Sickness Absence Clinic (NSAC) helps people with common mental health issues or muscle pain return to work faster. About 2500 adults will be split into three groups: one gets treatment within 4 weeks, another after 10-14 weeks, and a thir…

This study looks at how much muscle loss and fatigue breast cancer patients experience during and after radiation therapy. Researchers want to see if muscle loss happens in areas not directly treated by radiation, and whether it's linked to how tired patients feel. Twenty women w…