FATIGUE

This study is testing whether a structured physical activity program can help prevent colon cancer from coming back in people who have already had surgery and chemotherapy. It will compare a group that gets the exercise program plus health education to a group that gets health ed…

This study is testing different ways to help people at high risk for cancer or cancer survivors become more active and eat healthier foods. Researchers are comparing methods like weekly phone calls, emails, daily text messages, and online forums to see which combinations work bes…

This study is testing whether MitoQ, an antioxidant dietary supplement, can reduce fatigue in people with multiple sclerosis. Forty-five participants with MS and significant fatigue will take either MitoQ or a placebo pill daily for twelve weeks. Researchers will compare fatigue …

This study is testing if a lightweight, wearable leg exoskeleton can help reduce feelings of tiredness during everyday activities like walking and climbing stairs. Fifteen healthy adults over 65 will try the device during a series of mobility tasks. Researchers will measure how t…

This study tests a community health worker program called RESET, designed to help older adults in Detroit manage symptoms like depression, anxiety, chronic pain, and loneliness. Over 450 participants will join group phone calls, listen to podcasts, and use activity trackers to bu…

This study is testing whether adding electrical stimulation to leg muscles during standard pulmonary rehab helps people with COPD feel less short of breath and fatigued during activity, and more confident about exercising. It will involve 40 participants who have mild to severe C…

This study is testing whether combining physical activity with a short course of the steroid dexamethasone can reduce severe, persistent fatigue in people with advanced cancer. It will compare a high dose and a low dose of the steroid, both paired with a 4-week exercise program. …

This study is testing a web-based support program designed to help advanced cancer patients manage symptoms like depression, pain, and fatigue. It also aims to reduce stress and depression in their spouses or partners who are providing care. The program is intended to be accessib…

This small pilot study aims to see if chiropractic care is a practical and helpful way to reduce severe, long-lasting fatigue in adults who have finished their cancer treatment. Researchers will enroll 40 cancer survivors to test if the treatment is feasible and well-tolerated. T…

This study is testing two simple, non-drug methods to help people on hemodialysis feel less tired and sleep better. Researchers are comparing leg exercises and a special breathing device used during dialysis sessions to see which one works better. The goal is to find a safe, prac…

This UK trial is testing whether giving blood transfusions to intensive care unit (ICU) survivors with low red blood cell counts (anemia) helps them recover their strength and quality of life faster. It compares the current standard approach of giving fewer transfusions to a more…

This study is testing whether a simple relaxation exercise program can help people with type 2 diabetes feel better. Researchers are looking at 88 participants to see if guided muscle relaxation can reduce nerve pain and fatigue, and improve sleep quality. The goal is to provide …

This VA study is testing whether magnetic stimulation of the brain can help reduce the severe fatigue many people experience after a stroke. The trial will involve 60 stroke survivors who have been dealing with fatigue for over 6 months. Researchers will use a technique called re…

This small pilot study is testing whether a non-invasive brain stimulation technique called rTMS is safe and tolerable for people with Long COVID. Twenty participants with Long COVID, primarily suffering from fatigue and brain fog, will receive either real or sham (fake) stimulat…

This remote study aimed to provide holistic education and pastoral counseling to help people manage stress and improve wellness in daily life. It was designed for specific unmarried Alaska Medicaid recipients who met religious and lifestyle criteria. The study was withdrawn befor…

This study is testing whether acupressure and back massage can help women feel better after a cesarean section (C-section). Researchers want to see if these non-drug methods can reduce pain and tiredness, and help new mothers sleep better during recovery. The study involves 111 w…

This study aims to understand whether breast cancer patients lose muscle outside the radiation treatment area during radiotherapy, and if that muscle loss is connected to their fatigue. Researchers will follow 20 women with non-metastatic breast cancer, measuring their muscle via…

This study aims to understand how sleep problems contribute to heart and metabolic diseases in rural Southern communities. Researchers will measure the sleep patterns of about 3,680 adults from rural Appalachia and the Mississippi Delta using wearable devices and questionnaires. …

This study aims to understand how a 10-week exercise program might change the types of bacteria living in the gut of breast cancer survivors. Researchers will carefully control participants' diets and measure if changes in gut bacteria are linked to improvements in fatigue and ot…