FATIGUE

This study tests different programs to help people at high risk for cancer (such as those with BRCA or Lynch syndrome) or cancer survivors increase their physical activity and eat healthier. The goal is to see which programs work best to reduce cancer risk. About 337 participants…

This trial explores whether five daily sessions of a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can reduce fatigue in people who have had a stroke. Participants will receive either real or sham stimulation, and their fatigue levels wi…

This study looks at whether using the Calm meditation app for 10 minutes a day can help blood cancer patients who have trouble sleeping. Researchers will track sleep, mood, and inflammation in 276 participants over 20 weeks. The goal is to find a simple, drug-free way to improve …

This study tests whether a 12-week home exercise program, guided by telehealth check-ins, can reduce fatigue in cancer survivors living in rural Colorado. Participants follow a personalized plan of aerobic and resistance exercises, with intensity adjusted based on their progress.…

This study tests whether 16 weeks of aerobic exercise or cognitive behavioral therapy can reduce severe fatigue in people with myasthenia gravis, a muscle weakness condition. Sixty adults with stable MG will be randomly assigned to exercise, therapy, or usual care. The goal is to…

This study is testing whether a daily testosterone gel can reduce fatigue and improve sexual function in men aged 55 and older who have cancer and low testosterone. The trial involves 230 participants who will apply either the gel or a placebo for six months. Researchers will mea…

This study tests whether a 4-week educational program called 'Stay Awake, Stay Alive' can reduce drowsy driving among college students in Nevada. Participants attend weekly group sessions with role-plays, videos, and discussions, and track their sleep and driving. Researchers com…

This pilot study aimed to test whether immersive virtual reality (VR) exercises could help people with multiple sclerosis who experience dizziness, balance issues, and fatigue. Participants would have been randomly assigned to either VR-based vestibular rehab or conventional exer…

This study tests a mobile app called RN-SLEEP that teaches night-shift nurses cognitive-behavioral strategies to improve sleep and reduce fatigue. 76 nurses will use either the RN-SLEEP app or a control app for several weeks. Researchers will measure sleep duration, quality, and …

This study tests whether personalized coaching on physical activity and nutrition can reduce fatigue in people with lupus. 200 participants are split into two groups: one gets coaching on exercise and diet, the other gets general lupus education. The goal is to see if the coachin…

This pilot study explores whether chiropractic adjustments to the upper neck can reduce chronic fatigue in adults who have finished cancer treatment. About 40 cancer survivors who are currently cancer-free will receive either immediate or delayed chiropractic care for 6 to 12 wee…

This study tests whether adding a short course of the steroid dexamethasone to a physical activity program can better reduce severe fatigue in people with advanced cancer. About 90 participants will be randomly assigned to receive either a high or low dose of dexamethasone along …

This study tests whether acupressure (applying pressure to specific points on the body) and back massage can reduce pain, fatigue, and improve sleep quality in women recovering from a cesarean section. About 111 new mothers will receive these non-drug treatments after surgery. Th…

This study tests two simple activities—pedaling a stationary bike and using a breathing device—during dialysis sessions to see if they reduce fatigue and improve sleep. 102 adults on hemodialysis will be split into three groups: one does leg exercises, one does breathing exercise…

This study tests whether a lightweight leg exoskeleton called Exoband can reduce tiredness during daily tasks like walking, stair climbing, and crouching. Fifteen healthy adults aged 65 and older will perform these activities with and without the device. Researchers will measure …

This study looks at whether giving blood transfusions to patients who are anemic after leaving the intensive care unit (ICU) can help them feel less tired and recover better. About 346 adults from UK hospitals will be randomly assigned to either the usual care (transfusions only …

This study tests whether using a device that sends mild electrical pulses to the leg muscles can help people with COPD feel more confident about exercise, reduce shortness of breath during activity, and lessen fatigue. Forty patients with mild to severe COPD will receive the stim…

This study aims to better understand fatigue by comparing people who have felt tired for more than a month with those who are not fatigued. Researchers will use questionnaires, physical tests, and optional brain scans to identify different types of fatigue. The goal is to gather …

This study investigates why people with advanced chronic kidney disease (not yet on dialysis) often feel deep fatigue. Researchers will measure muscle strength and fatigue using simple tests like hand grip and walking speed. The goal is to understand how kidney disease affects ne…

This study looks at how tiredness (fatigue) affects the daily activities and quality of life of 89 children aged 2 to 18 who are being treated for cancer. Researchers will use special surveys to measure fatigue levels and see how they relate to the children's ability to do everyd…

This study tests whether a Norwegian clinic (NSAC) helps people with common mental health issues or muscle pain return to work sooner. 2500 adults are split into three groups: one gets treatment quickly, one waits 10-14 weeks, and one gets a basic check-up. Researchers will track…

This study looks at how joint flexibility, balance, and tiredness affect climbing performance in both elite and amateur climbers. Researchers will test 60 healthy climbers to see if flexible joints help or hurt, and how fatigue impacts reaction time and safety. The goal is to und…

This study tests whether giving doctors a summary of their patient's survey answers before a consultation helps people on sick leave return to work. About 1180 adults in Norway are taking part. The goal is to see if this simple nudge improves recovery and reduces time off work.

This study tracks 20 women with breast cancer to see if radiotherapy causes muscle loss outside the treated area and how it relates to fatigue. Participants complete fatigue questionnaires and get CT scans at four time points: start, end, and 1 and 3 months after treatment. The g…

This study was designed to test a holistic education program for stress management in people from colonized English-speaking countries. It aimed to help with conditions like stress, PTSD, anxiety, and fatigue using pastoral counseling and self-care activities. However, the study …

This study looks at how sleep problems like apnea, insomnia, and poor sleep quality are linked to heart disease and diabetes in rural southern areas. About 3,680 adults already in a larger health study will wear sleep trackers and answer questionnaires. The goal is to understand …

This study looks at how aerobic exercise changes the gut microbiome in breast cancer survivors and whether those changes relate to less fatigue. About 126 women who have finished primary treatment will take part. Researchers will measure gut bacteria from stool samples and track …