New trial: could walking and thinking beat fatigue in muscle disease?
NCT ID NCT06659627
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether 16 weeks of aerobic exercise or cognitive behavioral therapy can reduce severe fatigue in people with myasthenia gravis, a muscle weakness condition. Sixty adults with stable MG will be randomly assigned to exercise, therapy, or usual care. The goal is to see if these approaches improve fatigue scores enough to make a real difference in daily life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
aerobic exercise therapy and cognitive behavioural therapy
What this could lead to
If successful, this could offer drug-free ways to manage fatigue in myasthenia gravis, improving daily life.
What could go wrong
This is a small, early-stage trial (60 people) testing behavioral interventions, not a new drug. Results may not apply to all patients, and fatigue may not improve significantly.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Leiden University Medical Center
RECRUITINGLeiden, South Holland, 2333 ZA, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••