Testosterone gel trial aims to beat cancer fatigue in older men

NCT ID NCT04301765

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a daily testosterone gel can reduce fatigue and improve sexual function in men aged 55 and older who have cancer and low testosterone. The trial involves 230 participants who will apply either the gel or a placebo for six months. Researchers will measure changes in fatigue and sexual activity using standard questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

testosterone gel

What this could lead to

If it works, this could offer a way to ease fatigue and improve sexual health in older men with cancer who have low testosterone.

What could go wrong

This is a phase 2 trial, so results are still uncertain. Testosterone may not help fatigue, and there are risks like worsening prostate cancer or heart problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer eunuchism Fatigue hematopoietic and lymphoid cell neoplasm hypogonadism hypogonadism, male neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Georgia Cancer Center at Augusta University

    RECRUITING

    Augusta, Georgia, 30912, United States

    Contact

  • Veterans Affairs Puget Sound Health Care System

    RECRUITING

    Seattle, Washington, 98108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••