Hypogonadism, male
MONDO:0009421Also known as: hypogonadism, male, hypogonadism and testicular atrophy
21 clinical trials for this condition and its sub-types.
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New pill could boost testosterone in men with kidney disease
Disease control Recruiting nowThis study tests an oral testosterone pill called JATENZO in 20 men who have both low testosterone and chronic kidney disease. The goal is to see if the pill can raise testosterone levels and improve red blood cell counts, muscle strength, lean body mass, and sexual function. Par…
Phase: PHASE2 • Sponsor: St. Louis University • Aim: Disease control
Last updated Jun 27, 2026 12:26 UTC
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New testosterone injection could help teen boys with delayed puberty
Disease control Recruiting nowThis phase 3 trial is testing XYOSTED, a testosterone injection, in 100 adolescent males who lack or have low testosterone due to hypogonadism. The study lasts 52 weeks, with a 24-month safety follow-up, and aims to see if the treatment can safely induce or continue puberty. Part…
Phase: PHASE3 • Sponsor: Halozyme Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Testosterone trial aims to ease opioid side effects in men
Symptom relief Recruiting nowThis study tests whether giving testosterone to men with chronic back pain who take opioids can improve their pain, sexual function, fatigue, and quality of life. The men have low testosterone caused by opioids. Half will get testosterone injections and half a placebo. The trial …
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Testosterone shot may ease fatigue in young cancer survivors
Symptom relief Recruiting nowThis study tests whether a testosterone drug (Depo-Testosterone) can reduce fatigue and improve sexual function, mood, and body composition in young men (ages 18-54) who have survived cancer and now have low testosterone. Participants must be in remission for at least one year an…
Phase: PHASE2 • Sponsor: Seattle Institute for Biomedical and Clinical Research • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Testosterone shots aim to boost Well-Being in End-of-Life care
Symptom relief Recruiting nowThis study tests whether giving testosterone injections every 15 days can improve quality of life for men with low testosterone who are receiving best supportive care and have no further treatment options. Researchers will track symptoms like pain, fatigue, and daily living activ…
Phase: EARLY_PHASE1 • Sponsor: Jules Bordet Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Hormone implants could ease menopause symptoms for years
Symptom relief Recruiting nowThis study tests small hormone implants placed under the skin to relieve menopause symptoms like hot flashes, low mood, and sexual problems. It includes 140 women with natural menopause, early ovarian failure, or menopause from cervical cancer treatment. Researchers will check ho…
Phase: PHASE3 • Sponsor: University of Sao Paulo General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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600 men to help uncover hidden causes of low testosterone
Knowledge-focused Recruiting nowThis study will examine 600 men aged 35-59 in Uzbekistan to find out which physical, lifestyle, and emotional factors are linked to low testosterone. Participants will have blood tests, physical measurements, and complete questionnaires. The goal is to create a model that helps d…
Sponsor: Andijan State Medical Institute • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC
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Hidden heart risks in testicular cancer survivors: a closer look at chemotherapy's long shadow
Knowledge-focused Recruiting nowThis study investigates whether testicular cancer survivors who received cisplatin-based chemotherapy and bone marrow transplant have hidden heart disease that standard checkups might miss. Researchers will use advanced blood tests and CT scans to measure cholesterol, plaque in t…
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
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Finger clip could reveal hidden heart risks in men with ED
Knowledge-focused Recruiting nowThis study is testing whether a simple finger device called EndoPAT can measure blood vessel function in men aged 30–50 with erectile dysfunction or low testosterone. About 120 men will use the device before and after taking daily low-dose ED medication or testosterone therapy. T…
Phase: NA • Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Could low testosterone raise heart risk after spinal cord injury?
Knowledge-focused Recruiting nowThis study looks at why men with spinal cord injury often have low testosterone and how that might damage blood vessels, raising the risk of heart attacks and strokes. Researchers will test blood vessel function in 48 men with recent spinal cord injury and low testosterone. They …
Sponsor: Craig Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC