COLON CANCER

This study tests whether the drug cemiplimab can control a specific type of colon cancer (dMMR) that has not spread. About 50 adults will receive the drug to see if it can shrink or eliminate the tumor, potentially avoiding the need for surgery. The main goal is to check safety a…

This study is for people with early-stage colon cancer (stage I) who currently need a standard surgery that removes part of the colon. The new approach uses a special dye to find and remove only the tumor and the first lymph node, leaving more of the colon intact. The goal is to …

This early-phase study tests a new drug called RSC-1255, alone or with hydroxychloroquine, in adults with advanced solid tumors (like lung, colon, or pancreatic cancer) who have run out of standard treatments. The goal is to find a safe dose and see if the drug can control the di…

This study tests whether using virtual reality (VR) can reduce belly pain and improve daily life for people with digestive tract cancers. 360 participants will be randomly assigned to one of three groups: skills-based VR, distraction VR, or a sham VR. Researchers will track pain,…

This study looks at whether keeping the left colic artery intact during colorectal surgery for colon, rectal, or ovarian cancer helps maintain better blood flow to the colon. About 50 adults scheduled for surgery will have their colon's blood supply measured with and without clam…

This study is creating a large database of medical information and biological samples from adults with or at risk for many types of cancer, as well as healthy volunteers. The goal is to help researchers better understand what causes cancer, how it progresses, and how to improve p…

This study tests a new way to give radiation therapy to young women (ages 18-50) with cancers in the pelvic area, such as uterine or rectal cancer. The goal is to see if doctors can adjust the radiation each day to avoid hitting the ovaries, which could help preserve fertility an…