Engineered immune cells take on Hard-to-Treat cancers

NCT ID NCT06682793

First seen Oct 31, 2025 · Last updated Jun 12, 2026 · Updated 27 times

Summary

This study tests a new treatment called A2B395 for adults with advanced solid tumors like colorectal, lung, and breast cancer. The therapy uses specially designed immune cells to target and kill cancer cells while protecting healthy ones. The study has two parts: first finding a safe dose, then checking if it shrinks tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Banner MD Anderson Cancer Center

    RECRUITING

    Gilbert, Arizona, 85234, United States

    Contact Email: •••••@•••••

    Contact

  • Fred Hutch Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact

    Contact Email: •••••@•••••

  • Mayo Clinic

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact Phone: •••-•••-••••

    Contact

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-••••

    Contact

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33606, United States

    Contact Email: •••••@•••••

    Contact

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Email: •••••@•••••

    Contact

  • UCLA Medical Center

    RECRUITING

    Los Angeles, California, 90404, United States

    Contact

    Contact Email: •••••@•••••

  • UCSD Moores Cancer Center

    RECRUITING

    La Jolla, California, 92093, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Email: •••••@•••••

    Contact

Conditions

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