COLORECTAL ADENOCARCINOMA

This study is for people with advanced colorectal cancer that has a specific gene change called KRAS. The cancer has gotten worse after standard treatments. Researchers are testing if combining two drugs, AVUTOMETINIB and cetuximab, is safe and can shrink tumors. About 53 adults …

This study is testing a combination of three drugs (trastuzumab-deruxtecan, capecitabine, and bevacizumab) as a first treatment for people with a specific type of advanced colorectal cancer that has spread (HER-2 positive). The goal is to see how well this drug combo shrinks tumo…

This early-phase trial tests a new drug that delivers radiation directly to cancer cells by targeting a protein called Nectin-4. It is for people with advanced solid tumors (like bladder, breast, lung, or cervical cancer) that have not responded to prior treatments. The study aim…

This study tests a new type of CAR T cell therapy for adults with advanced solid tumors, including colorectal, pancreatic, lung, ovarian, and mesothelioma cancers. The treatment uses the patient's own immune cells, modified to target cancer cells while sparing healthy ones. The s…

This study aims to develop a simple blood test to detect colorectal cancer in people under 50, a group where cases are rising. Researchers will use tiny particles called exosomes and machine learning to find cancer signals. The goal is to catch the disease early without invasive …

This study is checking if a simple blood test can find tiny bits of tumor DNA left after treatment, which might help doctors know if colorectal cancer is likely to return. Researchers will collect blood samples from 1,000 adults with colorectal cancer who have finished or are abo…