New combo therapy targets hard-to-treat GI cancers

NCT ID NCT06065371

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests whether combining two drugs (sacituzumab govitecan and capecitabine) is safe for people with advanced gastrointestinal cancers that have stopped responding to standard treatments. About 20 adults with stomach, colorectal, or pancreatic cancer will take part. The goal is to find the best dose and see if a protein called Trop-2 can predict how well the treatment works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Biliary Tract Neoplasms colorectal adenocarcinoma colorectal cancer colorectal neoplasm digestive system cancer digestive system neoplasm esophageal adenocarcinoma esophageal cancer Esophageal Neoplasms gastric adenocarcinoma gastric cancer gastric neoplasm gastroesophageal adenocarcinoma gastroesophageal cancer gastroesophageal junction adenocarcinoma pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Henry Ford Cancer-Detroit

    RECRUITING

    Detroit, Michigan, 48201, United States

    Contact Email: •••••@•••••