New shot may help cancer patients keep weight during chemo

NCT ID NCT06937177

Recruiting now Symptom relief Sponsor: Endevica Bio Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times

Summary

This study tests a daily injection called TCMCB07 in 120 people with newly diagnosed colorectal cancer who are starting chemotherapy. The goal is to see if it can help maintain body weight and muscle mass, which often drop during treatment. Participants will receive either the study drug or a placebo for 12 weeks, and researchers will track weight changes and side effects.

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Conditions

The condition(s) this trial relates to.

Cachexia colorectal adenocarcinoma colorectal neoplasm pancreatic ductal adenocarcinoma pancreatic neoplasm Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER WEIGHT LOSS

Contacts and locations

Locations

Arizona Clinical Research Center
RECRUITING

Tucson, Arizona, 85715, United States
BRCR Global
RECRUITING

Tamarac, Florida, 33321, United States
Baptist Clinical Research
RECRUITING

Memphis, Tennessee, 38120, United States
Bioresearch Partners
RECRUITING

Hialeah, Florida, 33013, United States
Cancer Centers of Kansas
RECRUITING

Wichita, Kansas, 67214, United States
Cedars-Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Cross Cancer Institute
RECRUITING

Edmonton, Alberta, T6G 1Z2, Canada
D&H Cancer Research Center
RECRUITING

Margate, Florida, 33063, United States
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States
Hightower Clinical
RECRUITING

Oklahoma City, Oklahoma, 73102, United States
Hope and Healing Cancer Services
NOT_YET_RECRUITING

Hinsdale, Illinois, 60521, United States
Karmanos Cancer Center
RECRUITING

Detroit, Michigan, 48201, United States
Laguna Clinical Research Associates
RECRUITING

Laredo, Texas, 78041, United States
Life Clinical Trials
RECRUITING

Coral Springs, Florida, 33071, United States
Lumi Research
RECRUITING

Kingwood, Texas, 77090, United States
Medical University of South Carolina
NOT_YET_RECRUITING

Charleston, South Carolina, 29425, United States
Mt. Sinai Cancer Center
RECRUITING

Miami Beach, Florida, 33140, United States
NHO Revive Research Institute
RECRUITING

Lincoln, Nebraska, 68506, United States
NYU Langone Health Perlmutter Cancer Center
RECRUITING

New York, New York, 10016, United States
Nebraska Cancer Specialists
RECRUITING

Omaha, Nebraska, 68130, United States
Northwestern University - Robert H. Lurie Comprehensive Cancer Center
NOT_YET_RECRUITING

Chicago, Illinois, 60611, United States
Orchard Healthcare Research
RECRUITING

Skokie, Illinois, 60077, United States
Piedmont Healthcare Inc.
RECRUITING

Atlanta, Georgia, 30318, United States
UCLA Medical Center
RECRUITING

Santa Monica, California, 90404, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22908, United States
Vanderbilt-Ingram Cancer Center
NOT_YET_RECRUITING

Nashville, Tennessee, 37232, United States

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