Could a common numbing drug ease colon cancer surgery recovery?

NCT ID NCT06923787

Recruiting now Symptom relief Sponsor: Institute of Oncology Ljubljana Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving lidocaine (a numbing drug) through a vein during colon cancer surgery can reduce pain, lower the need for strong painkillers, and help the bowel start working sooner. One hundred adults undergoing laparoscopic colon cancer surgery will be randomly assigned to receive lidocaine or a placebo. The goal is to see if this simple addition can improve recovery without major side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine
What this could lead to: If it works, this could offer a simple, low-cost way to improve recovery after colon cancer surgery by reducing pain and opioid use.
What could go wrong: This is a small, early-phase trial. Lidocaine may not reduce pain or opioid use more than placebo, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colon carcinoma colonic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLON CANCER

Contacts and locations

Locations

Institute of Oncology Ljubljana
NOT_YET_RECRUITING

Ljubljana, 1000, Slovenia
Institute of Oncology Ljubljana
RECRUITING

Ljubljana, 1000, Slovenia

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