Institute Of Oncology Ljubljana

This study tests a treatment called electrochemotherapy for women whose vulvar cancer has come back. It combines a chemotherapy drug (bleomycin) with electric pulses to help the drug enter cancer cells more effectively. The goal is to shrink tumors and avoid major surgery. Only 1…

This study is testing a highly precise radiation method called SBRT for people with cancer that has spread to the spine. The goal is to deliver strong radiation doses while protecting nearby healthy tissue. Researchers will track side effects and how well the treatment controls t…

This study is testing whether adding a precise, high-dose form of radiation (SBRT) after standard chemotherapy can help control locally advanced pancreatic cancer that cannot be removed by surgery. Eighteen adults with this type of cancer will receive chemotherapy first, and if t…

This study tests whether giving lidocaine (a numbing drug) through a vein during colon cancer surgery can reduce pain, lower the need for strong painkillers, and help the bowel start working sooner. One hundred adults undergoing laparoscopic colon cancer surgery will be randomly …

This Phase 2 trial is testing whether giving lidocaine or high-dose dexamethasone during colon cancer surgery can improve the body's immune response and help patients recover better. 100 adults scheduled for colon cancer surgery will be randomly assigned to receive one of the two…

This study will follow 319 women with early-stage, hormone-sensitive, HER2-negative breast cancer to see how well they take their prescribed aromatase inhibitors, with or without the added drug abemaciclib. Researchers will measure adherence using pill counts and questionnaires a…

This study looks at how chemotherapy affects memory and thinking in people with a type of blood cancer called diffuse large B-cell lymphoma. Researchers will test cognitive function at the start, after the first chemo cycle, and one year later. They also analyze spinal fluid in s…

This study is testing a web-based application that lets cancer patients report side effects from radiation therapy in real time. The goal is to see if this tool helps doctors spot and address complications sooner. About 30 patients with gynecologic, urologic, or breast cancer wil…

This study follows 368 colorectal cancer survivors aged 25 to 65 to see how their quality of life changes 6, 12, and 24 months after treatment. Researchers will use questionnaires to measure physical, mental, and social well-being and look for late side effects linked to specific…

This study is tracking 100 people in Slovenia with advanced melanoma who are receiving first-line immunotherapy drugs like pembrolizumab, nivolumab, or ipilimumab. Researchers want to see how well these treatments work and whether a marker called PD-L1 in tumors or blood can pred…

This study looks at how much protein people with chronic intestinal failure need when they receive nutrition through a vein at home. The goal is to better understand their protein use and improve personalized nutrition mixtures. Researchers will also study gut bacteria and fatty …

This study is tracking 40 people in Slovenia with metastatic melanoma who are receiving standard first-line immunotherapy. Researchers want to see how well the treatment works and look for clues in blood, stool, and tumor samples that might predict who will benefit most. The goal…

This study is for people with high-risk early breast cancer, including inflammatory breast cancer. Researchers want to see if clusters of tumor cells found in the blood can help predict how well treatment works and the chances of survival. About 130 participants will give blood s…

This study looks at how electrochemotherapy—a treatment that uses electric pulses to help chemotherapy drugs enter cancer cells—changes the environment around melanoma skin tumors. Researchers will collect tissue samples from 150 adults before and after treatment to see how immun…

This study looks at how common muscle loss (sarcopenia) is in people with gastrointestinal cancer. Researchers will use a short questionnaire to screen patients before and during treatment. Those flagged as at risk will get extra nutritional support. The goal is to see if early d…