New combo therapy aims to tame tough pancreatic tumors
NCT ID NCT07407231
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether adding a precise, high-dose form of radiation (SBRT) after standard chemotherapy can help control locally advanced pancreatic cancer that cannot be removed by surgery. Eighteen adults with this type of cancer will receive chemotherapy first, and if their disease hasn't worsened, they'll get SBRT to the main tumor, followed by more chemo. The goal is to see how well the tumor responds and how long it takes for the cancer to progress.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
chemotherapy (e.g., FOLFIRINOX or gemcitabine plus nab-paclitaxel) followed by ablative stereotactic body radiotherapy (SBRT)
What this could lead to
If successful, this approach could offer a way to better control locally advanced pancreatic tumors, potentially delaying disease progression and improving outcomes without needing surgery.
What could go wrong
This is a very small, early-phase study (18 participants) with no control group, so results may not apply broadly. The combination of chemotherapy and radiation also carries risks of side effects like fatigue, nausea, and damage to nearby organs.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Institute of Oncology Ljubljana
RECRUITINGLjubljana, 1000, Slovenia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••