Institute Of Oncology Ljubljana
Clinical trials sponsored by Institute Of Oncology Ljubljana, explained in plain language.
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Stem cells offer hope for cancer survivors with chronic dry mouth
Disease control CompletedThis early study tested whether stem cells from donated umbilical cord tissue could help people with chronic dry mouth after radiation for head and neck cancer. Ten adults received a single injection of these stem cells and were monitored for safety and any improvement in saliva …
Phase: PHASE1 • Sponsor: Institute of Oncology Ljubljana • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Pressurized oxygen may heal radiation damage in cancer survivors
Disease control CompletedThis study tested whether hyperbaric oxygen therapy (HBOT) can help heal severe tissue damage caused by past radiation treatment. 39 adults who had radiotherapy and developed serious radiation injuries received HBOT sessions in a pressurized chamber while breathing pure oxygen. T…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Can a simple blood test replace tissue biopsies for lung cancer?
Diagnosis CompletedThis study looked at whether a blood test can find gene changes in people with advanced lung cancer. 22 adults gave a blood sample, and the results were compared to standard tissue tests. The goal was to see if the blood test is a reliable and practical option for guiding treatme…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Diagnosis
Last updated Jun 27, 2026 09:10 UTC
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New gene test may prevent unnecessary breast surgeries
Diagnosis CompletedThis study looked at whether testing for certain gene changes (methylation) can help doctors tell if a breast lesion is cancerous or not. 301 women with suspicious breast lumps had standard biopsies plus extra gene testing. The goal was to see if the gene test could improve diagn…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Diagnosis
Last updated Jun 27, 2026 09:07 UTC
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Breath sniffing device may spot head and neck cancer early
Diagnosis CompletedThis study tested a device called an 'artificial nose' that analyzes breath to detect head and neck cancer. 45 people (some with cancer, some healthy) gave breath samples. The device used sensors to create a unique breath pattern, aiming to tell who had cancer and who did not.
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Diagnosis
Last updated Jun 27, 2026 09:07 UTC
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New gene test may spot hidden breast cancer in Hard-to-Diagnose lesions
Diagnosis CompletedThis study looked at whether checking for certain gene changes (methylation of BRCA1, RASSF1A, and PTEN) in breast tissue samples can help doctors tell the difference between harmless and cancerous breast lesions. Researchers tested tissue from 401 women with breast lesions that …
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Diagnosis
Last updated Jun 27, 2026 09:07 UTC
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New ultrasound tricks could sharpen breast cancer staging
Diagnosis CompletedThis study tested whether adding two special ultrasound techniques—elastography and contrast-enhanced ultrasound—can better detect breast cancer spread to underarm lymph nodes. Researchers studied 180 women with breast cancer to see if these extra scans improve accuracy compared …
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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New blood tests could speed up detection of deadly fungal infections
Diagnosis CompletedThis study looked at whether combining several blood tests can detect serious fungal infections (candidemia) faster and more accurately than standard methods. Researchers tested 2 hospitalized adults with suspected fungal infections using both routine blood cultures and newer tes…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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New pump could ease cancer pain without heavy drugs
Symptom relief CompletedThis study tested an implantable pump that delivers pain medicine directly into the spinal fluid for people with hard-to-treat cancer pain. Eight patients with advanced cancer and severe pain despite strong opioids took part. The goal was to see if the pump could provide better p…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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New rehab program aims to ease life after colorectal cancer
Symptom relief CompletedThis study tested a personalized rehabilitation program for 150 adults who finished treatment for colorectal cancer. The program connects patients with specialists like physiotherapists, dietitians, and psychologists based on their individual needs. The goal was to improve qualit…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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New radiotherapy method for breast cancer shows promise in reducing side effects
Symptom relief CompletedThis study looked at side effects from a special radiotherapy technique called simultaneous integrated boost (SIB) given after breast-conserving surgery for breast cancer. 93 women were followed to see how well they tolerated the treatment. The goal was to compare side effects wi…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Hidden muscle loss common in GI cancer patients, study finds
Knowledge-focused CompletedThis study looked at how many people with gastrointestinal cancer are at risk for sarcopenia, a condition where muscle mass and strength are lost. Researchers used a simple questionnaire called SARC-F to screen 44 patients before and during cancer treatment. The goal was to ident…
Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Childhood brain tumor survivors face hidden hormone risks
Knowledge-focused CompletedThis study examined 12 childhood brain tumor survivors to understand long-term hormone and metabolic problems. Researchers checked for issues like growth hormone deficiency, thyroid problems, obesity, and abnormal cholesterol. The goal is to help doctors better monitor and manage…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Melanoma Drug's eye impact revealed in new study
Knowledge-focused CompletedThis study looked at 14 adults with melanoma who were taking a combination of BRAF and MEK inhibitor drugs. The goal was to understand how these drugs can affect the retina, the light-sensitive part of the eye. Researchers used eye exams and special imaging to track changes over …
Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Biomarker hunt: could IFN-Gamma guide melanoma treatment?
Knowledge-focused CompletedThis completed study looked at 132 people with advanced melanoma to see if levels of a protein called interferon-gamma (IFN-γ) in their tumors or blood could predict how well they would respond to first-line immunotherapy drugs like pembrolizumab, nivolumab, or a combination. The…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Blood clues: new study looks at tumor cells in ovarian cancer
Knowledge-focused CompletedThis study looked at 30 women with advanced ovarian cancer to count and examine tumor cells found in their blood. The goal was to see if these cells could help predict how the disease might progress or respond to treatment. The results may lead to better ways to monitor the disea…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Urine and blood may hold key to kidney cancer treatment response
Knowledge-focused CompletedThis study explored whether small particles called exosomes, found in blood and urine, can help predict how well treatment works in people with advanced kidney cancer. Researchers followed 91 patients for 16 weeks, collecting samples and comparing them to imaging results. The goa…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Melanoma drug side effects on eyes revealed in new study
Knowledge-focused CompletedThis study examined 30 people with melanoma who were taking BRAF/MEK inhibitor drugs to see how often these drugs cause retinal changes (MEKAR) and what those changes look like. Participants had regular eye exams before, during, and after treatment. The goal was to better underst…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Teens quizzed on cancer risks: results to shape future prevention
Knowledge-focused CompletedThis study asked 795 teenagers in Slovenia, aged 12 to 18, to fill out a questionnaire about cancer risk factors. The goal was to see how much they already know so that better health education can be designed. No treatment or prevention was given—just a survey to gather informati…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Custom 3D printed devices aim to improve cancer radiation delivery
Knowledge-focused CompletedThis study tested whether custom 3D printed applicators could improve radiation delivery in brachytherapy for gynecological cancers. Thirteen patients with cervical, uterine, vaginal, or vulvar cancer received MRI-guided treatment using these personalized tools. The goal was to s…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Brain tumour study: could your mood and memory predict survival?
Knowledge-focused CompletedThis completed study looked at 90 adults with glial brain tumours to see if their quality of life and thinking abilities (like memory and focus) could help predict how long they live. Researchers used questionnaires and cognitive tests to track changes over time. The goal is to h…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Researchers watch how SBRT works for liver and pancreatic tumors
Knowledge-focused CompletedThis study looked at how safe and effective a precise type of radiation therapy (SBRT) is for treating liver tumors, liver metastases, and pancreatic tumors. It involved 65 adult patients who were already scheduled for SBRT. The goal was to monitor and improve the treatment proce…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Immune clues in breast tumors could forecast chemo outcomes
Knowledge-focused CompletedThis study looked at 171 women with early breast cancer to see if immune cells inside tumors are linked to how well chemotherapy works. Researchers also checked if certain markers in the blood could help predict cancer return. The goal was to better understand which patients migh…
Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Phone Check-Ins track prostate cancer in men with BRCA mutations
Knowledge-focused CompletedThis study followed 25 men who carry BRCA1 or BRCA2 gene mutations (and a control group of non-carriers) to see if they developed prostate cancer. Researchers called participants to update their medical history and check for new diagnoses. The goal is to learn how to better scree…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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MRI may sharpen radiation aim in esophageal cancer
Knowledge-focused CompletedThis study looked at whether using MRI scans can reduce differences in how doctors outline esophageal cancer tumors for radiation therapy. Twenty-three patients with advanced esophageal cancer had MRI scans in addition to standard CT and PET/CT scans. Five radiation oncologists i…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Gut bugs may influence cancer treatment success
Knowledge-focused CompletedThis study looked at 58 head and neck cancer patients receiving standard radiotherapy. Researchers collected stool and blood samples to see if gut bacteria and their byproducts are linked to how well the treatment works and how severe side effects are. The goal is to find clues t…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Surgery's hidden toll: new study tracks quality of life in gynecologic cancer survivors
Knowledge-focused CompletedThis completed study followed 40 women who had standard surgery for gynecologic cancers (endometrial, cervical, ovarian, or fallopian tube). Researchers measured changes in quality of life and checked for lower limb lymphedema (leg swelling). The goal was to learn how surgery aff…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Urine and blood clues may predict kidney cancer treatment success
Knowledge-focused CompletedThis study involved 91 adults with advanced kidney cancer. Researchers collected blood and urine samples over 16 weeks to see if changes in tiny particles called exosomal miRNAs could predict whether treatment was working. The goal was to find a simple, non-invasive way to monito…
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC